Photoactivation of trans diamine platinum complexes in aqueous solution and effect on reactivity towards nucleotides [PDF]
We show that UVA irradiation (365 nm) of the Pt-IV complex trans,trans,trans-[(PtCl2)-Cl-IV(OH)(2)(dimethylamine) (isopropylamine)] (1), induces reduction to Pt-II photoproducts.
Pizarro, Ana M. +5 more
core +1 more source
Envolvimento dos receptores NMDA e da via L-arginina-óxido nítrico-GMPc no efeito tipo-antidepressivo da guanosina [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.A guanosina é um nucleosídeo endógeno que modula a captação de glutamato pelos astrócitos, controlando os níveis ...
Bettio, Luis Eduardo Beltrão
core
Are guanine nucleotide-binding proteins involved in regulation of thylakoid protein kinase activity?
The slow ATP-induced decrease in chlorophyll fluorescence associated with the phosphorylation of LHC II seen in spinach thylakoids was inhibited by GTP and its non-hydrolysable analogues β, γ-imidoguanosine 5′-triphosphate and guanosine 5′-O-(3 ...
Paul A. Millner, Millner, Paul A.
core +1 more source
The breakdown of exogenously added [3H]inositol-labeled phosphoinositides by rat brain cortical membranes was stimulated by the muscarinic cholinergic agonist carbachol. The stimulation required the presence of guanine nucleotide. Optimal conditions were similar to those described for guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) + carbachol ...
E, Claro +3 more
openaire +2 more sources
O nucleosídeo guanosina promove neuroproteção contra o estresse oxidativo e bioenergético em um modelo de isquemia cerebral in vitro [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2015As doenças vasculares cerebrais isquêmicas representam uma importante causa de mortalidade no ...
Thomaz, Daniel Tonial
core
Glutamate-Stimulated, Guanine Nucleotide-Mediated Phosphoinositide Turnover in Astrocytes Is Inhibited by Cyclic AMP [PDF]
The potential for cross-talk between the adenyl cy-clase and phosphoinositide (PPI) lipid second messenger system was investigated in astrocytes cultured from neonatal rat brain.
George R. Bruno +5 more
core +1 more source
An Effector of Hemoglobin Structure: The Guanosine 3', 5'-Triphosphate
The effect of guanosine 3', 5'-triphosphate (GTP) on the hemoglobin structure was studied by UV-visible, fluorescence and circular dichroism (CD) spectroscopies, and cyclic voltammetry.
Arefi, Mohammad Reza +11 more
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The guanine nucleotide regulatory protein component (N) of the frog erythrocyte membrane adenylate cyclase system appears to form a stable complex with the beta-adrenergic receptor (R) in the presence of agonist (H). This agonist-promoted ternary complex HRN can be solubilized with Lubrol.
J M, Stadel +3 more
openaire +2 more sources
Guanosine 5'-O-(3-thio)triphosphate (GTP gamma S) is a good analog of GTP in the reactions leading to the formation of a peptide bond in protein biosynthesis. It forms binary and ternary complexes with elongation factor Tu (EF-Tu), and with EF-Tu and aminoacyl-tRNA (aa-tRNA). In addition, it stimulates aa-tRNA binding to ribosomes. Although GTP gamma S
A M, Karim, R C, Thompson
openaire +2 more sources
Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
Although there are some data concerning the nitric oxide and the cyclic 3'-5'guanosine monophosphate (cGMP) signaling pathway in trypanosomatids, there is no report about the cGMP-dependent enzymatic activity identification.
Géigel, LF +5 more
core +2 more sources

