Results 61 to 70 of about 6,222 (140)

Estudo dos mecanismos da neuroproteção promovida pela guanosina em fatias de hipocampo de ratos submetidas à privação de glicose e oxigênio [PDF]

open access: yes, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Os derivados da guanina têm sido implicados em vários efeitos extracelulares, como a modulação do sistema ...
Dal-Cim, Tharine Aparecida
core  

Characterization of melatonin receptors and signal transduction system in rat arteries forming the circle of Willis

open access: yes, 1994
The aims of this study were to characterize the melatonin receptors in rat brain arteries forming the circle of Willis. Saturation studies performed using in vitro autoradiography and [I-125]iodomelatonin revealed the presence of two binding sites: one ...
SAAVEDRA JM   +3 more
core   +1 more source

Guanosine-based Nucleolipids: Design, Synthesis and Gelling Properties

open access: yes, 2010
A mini-library of amphiphilic guanosine derivatives, functionalized with fatty acids or lipid derivatives at the 2’ and 3’-OH moieties and incorporating different hydrophilic group at the 5’-OH position, has been prepared to study their self-assembly
D. Milano   +4 more
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Urinary excretion of cyclic adenosine 3',5'-monophosphate and cyclic guanosine 3',5'-monophosphate in malignancy

open access: yes, 1978
The urinary excretion of cyclic adenosine 3',5'-monophosphate (cAMP), corrected for urinary creatinine, was determined in 177 patients with primary or metastatic tumours and in 149 normal subjects.
Galli, M.   +3 more
core   +1 more source

Leukotriene C4 binds to receptors and has positive inotropic effects in bullfrog heart. Journal of Pharmacology and Experimental Therapeutics

open access: yes, 1991
ABBREVIATIONS: LT, leukotnene; dT/dt, derivative of developed tension over time; B,,,.
Matt Chiono   +3 more
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In Search of Enzymes with a Role in 3′, 5′-Cyclic Guanosine Monophosphate Metabolism in Plants

open access: yes, 2016
In plants, nitric oxide (NO)-mediated 3′, 5′-cyclic guanosine monophosphate (cGMP) synthesis plays an important role during pathogenic stress response, stomata closure upon osmotic stress, the development of adventitious roots and transcript ...
Jörg Durner   +3 more
core   +1 more source

Inhibition of the voltage-dependent calcium current by extracellular ATP in hamster ventricular cardiomyocytes

open access: yes, 1997
The modulation of the high-voltage-activated calcium current (ICa) by external ATP was examined in single ventricular cardiomyocytes of the hamster using the whole-cell configuration of the patch-clamp technique.
B. D. Gonska   +2 more
core   +1 more source

Conformational studies of the smallest structural motifs of DNA detectable via vibrational circular dichroism: cytidylyl-(3'-5')-guanosine and guanylyl-(3'-5')-cytidine

open access: yes, 1995
The infrared absorption and vibrational circular dichroism (VCD) spectra of buffered aqueous solutions of cytidylyl-(3'-5')-guanosine (5'(CG)3') and guanylyl-(3'-5')-cytidine (5'(GC)3') are reported.
Diem, M., Birke, S.S.
core   +1 more source

Estudo dos efeitos neuroprotetores e neurotóxicos dos derivados da guanina em fatias de hipocampo de ratos e em culturas de células de neuroblastoma humano SHSY-5Y [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Neurociências, Florianópolis, 2009Avaliação do efeito neuroprotetor de guanosina-5'-monofosfato (GMP) e guanosina frente à ...
Molz, Simone
core  

ARF-independent inhibition of the carbachol-induced contractions by brefeldin A in intestinal smooth muscle

open access: yes, 1997
The aim of this study was to determine whether an ADP ribosylation factor (ARF)-regulated pathway is involved in the carbachol-induced contraction in rat intestinal smooth muscle. Brefeldin A, a known inhibitor of the guanine nucleotide exchange activity
G. Loirand   +3 more
core   +1 more source

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