Results 71 to 80 of about 37,457,458 (124)

SuFEx chemistry for nucleosides, nucleotides, and nucleic acids. [PDF]

RSC Chem Biol
Chromiński M, Żmudziński M, Jemielity J.   +2 more
europepmc   +1 more source

In vitro and in vivo pharmacological characterization of fentanyl analogs. [PDF]

Neuropharmacology
Obeng S, Urquhart KR, Fukuda S, Pallares VLC, McMahon LR, Fantegrossi WE, Hiranita T.   +6 more
europepmc   +1 more source

Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB₁ and CB₂ receptors. [PDF]

Eur J Med Chem, 2023
Kline T, Xu C, Kreitzer FR, Hurst DP, Eldeeb KM, Wager-Miller J, Olivas K, Hepburn SA, Huffman JW, Mackie K, Howlett AC, Reggio P, Stella N.   +12 more
europepmc   +1 more source

ATPase-dependent duplex nucleic acid unwinding by SARS-CoV-2 nsP13 relies on facile binding and translocation along single-stranded nucleic acid. [PDF]

J Biol Chem
Park J, Jeong YJ, Chauhan K, Koh HR, Kim DE.   +4 more
europepmc   +1 more source

An artificial cell capable of signal transduction mediated by ADRB2 for the regulation of glycogenolysis. [PDF]

Nat Commun
Liu Y, Zhao W, Zhao Y, Zhang X, Zhao J, Li S, Ren Y, Han X.   +7 more
europepmc   +1 more source

Reconstitution of microtubule into GTP-responsive nanocapsules. [PDF]

Nat Commun, 2022
Uchida N, Kohata A, Okuro K, Cardellini A, Lionello C, Zizzi EA, Deriu MA, Pavan GM, Tomishige M, Hikima T, Aida T.   +10 more
europepmc   +1 more source

ATPγS substantially defeats the biasing mechanism for kinesin steps. [PDF]

Nat Commun
Karnawat V, Toleikis A, Carter NJ, Molloy JE, Cross RA.   +4 more
europepmc   +1 more source

Cannabinoid Receptors and Glial Response Following a Basal Forebrain Cholinergic Lesion. [PDF]

ACS Pharmacol Transl Sci, 2022
Llorente-Ovejero A, Bengoetxea de Tena I, Martínez-Gardeazabal J, Moreno-Rodríguez M, Lombardero L, Manuel I, Rodríguez-Puertas R.   +6 more
europepmc   +1 more source

2'-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity.

Recognition of RNA fragments by Toll-like receptor 7 (TLR7) and TLR8 helps to initiate the innate immune response against pathogens. An outstanding question is why RNA fragments generated during clearance of apoptotic cells fail to activate TLR7 and TLR8
Erandi Rupasinghe (23701572), Lorna Wilkinson-White (171599), Hani Hosseini Far (23701581), Julia I Ellyard (17026845), Mary Speir (20045985), W Samantha N Jayasekara (17026815), Rui Gao (247606), Claudia A Nold-Petry (13595455), Ben Corry (135521), Le Ying (1540618), Carola Vinuesa (11406968), Toshiyuki Shimizu (413452), Rasan M Sathiqu (23701578), Paul J Hertzog (13596694), Josiah Bones (17614566), Roland Gamsjaeger (19681561), Alexandra L McAllan (23701575), Olivier F Laczka (17026854), Refaya Rezwan (17026839), Kim A Lennox (23701587), Liza Cubeddu (157177), Daniel S Wenholz (17026818), Umeharu Ohto (783558), Zhikuan Zhang (12999815), Sunil Sapkota (9708095), Michael P Gantier (7948472), Dingyi Yu (2413507), Sitong He (18496135), Arwaf S Alharbi (17026836), Cameron R Stewart (23701590), Ruitao Jin (8978840), Marina R Alexander (23701584), Mark A Behlke (16255670)   +32 more
core  

Novel Ligands for the Orphan Receptor GPR151 Modulate Morphine Action. [PDF]

Genes Cells
Yoshida H, Suto T, Hirano H, Osada H, Nunomura K, Lin B, Saito S, Takeda S.   +7 more
europepmc   +1 more source