Results 91 to 100 of about 6,222 (140)

Synthesis and Pharmacological Characterization of a Novel Cannabinoid Receptor 1 Antagonist. [PDF]

ACS Omega
Bengoetxea de Tena I, Pereira-Castelo G, Martínez-Gardeazabal J, Moreno-Rodríguez M, Manuel I, Martínez C, Vaz B, González-Ricarte J, Álvarez R, Torres-Mozas A, Peccati F, Jiménez-Osés G, Rodríguez de Lera A, Rodríguez-Puertas R.   +13 more
europepmc   +1 more source

Exploring Reactions Between Substituted-Aromatic Aldehydes and Guanosine

, 2017
The reactivity of substituted-aromatic aldehydes with guanosine and arginine can help elucidate information about how these chemicals could react within our bodies.
Kim, Dahye
core  

Rapid purification of brain protein complexes containing active and inactive forms of the G protein Gαo. [PDF]

PLoS One
Yadav S, Veliventi SS, Meena S, Koelle MR, Kumar S.   +4 more
europepmc   +1 more source

In vitro and in vivo pharmacological characterization of fentanyl analogs. [PDF]

Neuropharmacology
Obeng S, Urquhart KR, Fukuda S, Pallares VLC, McMahon LR, Fantegrossi WE, Hiranita T.   +6 more
europepmc   +1 more source

Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB₁ and CB₂ receptors. [PDF]

Eur J Med Chem, 2023
Kline T, Xu C, Kreitzer FR, Hurst DP, Eldeeb KM, Wager-Miller J, Olivas K, Hepburn SA, Huffman JW, Mackie K, Howlett AC, Reggio P, Stella N.   +12 more
europepmc   +1 more source

Guanosine 5'-diphosphate 3'-diphosphate (ppGpp), guanosine 5'-diphosphate 3'-monophosphate (ppGp) and antibiotic production in Streptomyces clavuligerus

Streptomyces clavuligerus was grown in nutrient-limited defined media in laboratory scale fermenters using continuous and batch culture methods. Cephamycin C was produced in all fermentations.
Jones, Christine
core  

New guanosine 5’-phosphate derivatives as flavor enhancers

, 2009
A number of N2 -alkyl and N2 -acyl derivatives of guanosine 5’-phosphate (2 and 3) have been synthesized as potential flavor enhancers and tested for their synergistic effect with monosodium-L-glutamate (MSG), the prototypical substance imparting umami ...
G. Speranza, P. Manitto, C.F. Morelli
core  

ATPase-dependent duplex nucleic acid unwinding by SARS-CoV-2 nsP13 relies on facile binding and translocation along single-stranded nucleic acid. [PDF]

J Biol Chem
Park J, Jeong YJ, Chauhan K, Koh HR, Kim DE.   +4 more
europepmc   +1 more source

Reconstitution of microtubule into GTP-responsive nanocapsules. [PDF]

Nat Commun, 2022
Uchida N, Kohata A, Okuro K, Cardellini A, Lionello C, Zizzi EA, Deriu MA, Pavan GM, Tomishige M, Hikima T, Aida T.   +10 more
europepmc   +1 more source

Influence of acetyl and bromine substitutions on stacking. Crystal and molecular structures of 8-bromo-2',3',5'-triacetyl adenosine and 8-bromo 2',3',5'-triacetyl guanosine

, 1992
The three dimensional structures of 8-bromo 2',3',5' triacetyl adenosine (8-Br Tri A) and 8-bromo 2',3',5'-triacetyl guanosine (8-Br Tri G) have been determined by single crystal X-ray diffraction methods to study the combined effect of bromine and ...
Viswamitra, MA, Ramakumar, S, Lalitha, HN, Mande, Sharmila S   +3 more
core