Structure-guided engineering of a polyphosphate kinase 2 class III from an <i>Erysipelotrichaceae</i> bacterium to produce base-modified purine nucleotides. [PDF]
Mitton-Fry RM +7 more
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Microbial Primer: what is the stringent response and how does it allow bacteria to survive stress? [PDF]
Urwin L, Savva O, Corrigan RM.
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The capping arms race: evolutionary interplay between IFIT proteins and viral molecular mimicry. [PDF]
González-Hilario S +3 more
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A novel stationary phase approach for improved recombinant protein expression in Escherichia coli: beyond the exponential phase. [PDF]
Kang YH +7 more
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Profiling Nucleotide Signalling Pathways and STING Agonist Activity with a Nucleotide Library
Bekere I +4 more
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Accumulation of guanosine tetraphosphate induced by polymixin and gramicidin in Escherichia coli
The effects of two polypeptide antibiotics, polymixin B and gramicidin S, on the intracellular pool size and turnover of guanosine tetraphosphate (ppGpp) were analyzed in stringent (relA+) and relaxed (relA) strains of Escherichia coli. When either one of these two drugs was added to stringent bacteria cultures at a final concentration that blocked ...
Jean-Claude Cortay +2 more
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Accumulation and turnover of guanosine tetraphosphate in Escherichia coli
Journal of Molecular Biology, 1972Abstract A strain ofEscherichia coli B possessing a temperature-labile valyl-transfer RNA synthetase (strain NF 342) has been used to study guanosine tetraphosphate metabolism. Culturing this strain at a variety of temperatures intermediate between the permissive and non-permissive (30 to 42 °C) yielded a range of growth rates, presumably as a result
Kaspar Von Meyenburg +2 more
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