Results 111 to 120 of about 162,062 (330)
Frontiers in Physiology, 2015 Aquatic and semiaquatic mammals have the capacity of breath hold (apnea) diving. Northern elephant seals (Mirounga angustirostris) have the ability to perform deep and long duration dives; during a routine dive, adults can hold their breath for 25 min ...
Myrna eBarjau Perez-Milicua +3 more
doaj +1 more source
What are guanosine triphosphate-binding proteins doing in mitochondria?
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1998 The discovery of GTP-binding proteins in mitochondria is a recent event. These regulatory proteins may be participating in membrane fusion and thereby playing important roles in the physiology of the mitochondrion. So far, it has been proposed that GTP-binding protein mediated membrane fusion may be involved in protein import, steroid hormone ...
openaire +3 more sources
Assignments of backbone 1H, 13C and 15N resonances in H-Ras (1–166) complexed with GppNHp at physiological pH [PDF]
, 2012 The small GTPase Ras is an important signaling molecule acting as a molecular switch in eukaryotic cells. Recent findings of global conformational exchange and a putative allosteric binding site in the G domain of Ras opened an avenue to understanding ...
Kovriguine, Evgueni, O\u27Connor, Casey
core +1 more source
Roles of ion channels in immune cells [PDF]
, 2016 The Editorial on the Research Topic - Roles of Ion Channels in Immune ...
Amanda eMacKenzie +5 more
core +3 more sources
Blood, 1993 Gunmetal (gm/gm) is a recessively inherited mouse pigment dilution mutant that has high mortality and poor reproductive rates. In these studies, several hematologic defects were found associated with the mutation, including prolonged bleeding times ...
R. Swank +6 more
semanticscholar +1 more source
Nonequilibrium Self‐Assembly of Microtubules Through Stepwise Sequential Interactions of DNA
Small, EarlyView.This study presents a molecular swarm system activated through stepwise DNA interactions. DNA‐tethered microtubules exchange signals via specific sequence recognition, enabling sequential assembly and communication. This innovative approach advances autonomous molecular machine development, offering potential for adaptive, active, and complex ...
Jakia Jannat Keya +6 more
wiley +1 more source
Molecules, 2018 The construction of supramolecular recognition systems based on specific host–guest interactions has been studied in order to design selective chemical sensors. In this study, guest-responsive receptors for ATP have been designed with cyclodextrins (CyDs)
Tatsuru Yamada +5 more
doaj +1 more source
Clinical Evaluation of Potential Interaction Between Bemnifosbuvir and Ruzasvir With an Assessment of Food Effect: Results of a Phase 1 Study in Healthy Participants. [PDF]
Clin Pharmacol Drug DevAbstract A combination of nucleotide hepatitis C virus (HCV) nonstructural protein (NS) 5B and 5A inhibitors is a preferred standard of care for treating chronic HCV. Bemnifosbuvir is a novel oral guanosine nucleotide prodrug with potent pan‐genotypic inhibitory activity against HCV NS5B.
Zhou XJ +7 more
europepmc +2 more sources
Specific ATP Detection Using Molecule‐Responsive DNA Nanopores
Small, EarlyView.A molecule‐responsive DNA nanopore that provides open/close states by the interaction between an aptamer and analytes is rationally designed. This paper shows the applicability of DNA nanopores for stochastic nanopore sensing by revealing analyte‐concentration dependency, voltage‐dependency, and open/close mechanism.
Hiromu Akai +3 more
wiley +1 more source
Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response
Microbial Cell, 2019 In our recent publication (Zhang et al., 2019), we demonstrate an interesting mode of regulation of purine metabolism unique to Proteobacteria. In this microreview, we would like to reflect on the ideas put forward, with special focus on protein domain ...
René Lysdal Bærentsen +2 more
doaj +1 more source