Results 111 to 120 of about 84,847 (305)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Ferroptosis resistance is a key player in cervical cancer (CC) development. Hypoxia is a negative factor affecting CC treatment by inducing ferroptosis resistance. Our study aimed to investigate the detailed mechanisms of hypoxia‐induced ferroptosis resistance in CC cells.
Yan Gao, Ting Zou
wiley +1 more source
mRNA cap regulation in mammalian cell function and fate [PDF]
, 2019 In this review we explore the regulation of mRNA cap formation and its impact on mammalian cells. The mRNA cap is a highly methylated modification of the 5’ end of RNA pol II-transcribed RNA.
Cowling, Victoria, Galloway, Alison
core +2 more sources
Human Cyclophilins—An Emerging Class of Drug Targets
Medicinal Research Reviews, EarlyView.ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Post-Translational Modification and Subcellular Distribution of Rac1: An Update
Cells, 2018 Rac1 is a small GTPase that belongs to the Rho family. The Rho family of small GTPases is a subfamily of the Ras superfamily. The Rho family of GTPases mediate a plethora of cellular effects, including regulation of cytoarchitecture, cell size, cell ...
Abdalla Abdrabou, Zhixiang Wang
doaj +1 more source
A phased-addition strategy enhances the yield of RNAs obtained by in vitro transcription with modified transcriptional initiators [PDF]
, 2015 RNA is active in multiple biological processes, not only as an information carrier but in catalyzing reactions and regulating gene expression. To understand the basis for this versatility, it is critical to establish structure-function relationships in ...
Adib, Katie
core
Small Structures, EarlyView.Flexoelectric polarization is harnessed to dynamically enhance phosphatase‐mimicking catalysis in Gd‐based nanoflowers, enabling ultrasound‐responsive and efficient biophosphate ester hydrolysis through strain‐induced electronic modulation. Phosphatase‐mimicking nanozymes provide highly stable enzyme‐like activity but remain limited by their static ...
Linjing Su +7 more
wiley +1 more source
Molecular Therapy: Methods & Clinical Development, 2019 We developed a novel chemically modified miR-143 (miR-143#12), and with it we investigated the contribution of miR-143 to the pathogenesis of bladder cancer (BC), in which miR-143 is extremely downregulated.
Yuki Yoshikawa +11 more
doaj +1 more source
Postulates on electromagnetic activity in biological systems and cancer [PDF]
, 2013 A framework of postulates is formulated to define the existence, nature, and function of a coherent state far from thermodynamic equilibrium in biological systems as an essential condition for the existence of life. This state is excited and sustained by
Alberts +69 more
core +1 more source
Journal of Biological Chemistry, 1966 Abstract The rabbit reticulocyte is capable of utilizing purines and their ribosyl derivatives for nucleoside triphosphate formation. Adenine, adenosine, hypoxanthine, and inosine are used extensively for the synthesis of adenosine triphosphate. Xanthine, guanine, and guanosine are utilized primarily for the synthesis of guanosine triphosphate.
J L, Cook, M, Vibert
openaire +2 more sources
DNA Nanostructure‐Guided Synthesis of Nanomaterials and Their Applications
Small Structures, EarlyView.This review summarizes the state‐of‐the‐art progress on the synthesis of nanomaterials, e.g., inorganic nanomaterials, organic polymers, and liposomes, based on DNA templates, and several emerging applications of these nanomaterials are also included.
Yiming Xie +3 more
wiley +1 more source