Human granulocyte colony-stimulating factor specifically binds to murine myeloblastic NFS-60 cells and activates their guanosine triphosphate binding proteins/adenylate cyclase system [PDF]
, 1989 Sachiko Matsuda +2 more
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Biotechnology and Bioengineering, Volume 122, Issue 9, Page 2456-2464, September 2025.The authors present a streamlined cascade reaction for one‐pot N‐C rearrangement of uridine‐5′‐phosphate (UMP) to pseudouridine‐5′‐phosphate (ΨMP; a key mRNA vaccine building block), in two enzymatic steps catalyzed by UMP nucleosidase (EC 3.2.2.10) and ΨMP C‐glycosidase (EC 4.2.1.70).
Martin Pfeiffer +2 more
wiley +1 more source
Evidence that guanosine triphosphate (GTP)-binding proteins control a synaptic response in brain: effect of pertussis toxin and GTP gamma S on the late inhibitory postsynaptic potential of hippocampal CA3 neurons [PDF]
, 1988 R. H. Thalmann
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Delivering the Message: Translating mRNA Therapy for Liver Inherited Metabolic Diseases
Journal of Inherited Metabolic Disease, Volume 48, Issue 5, September 2025.ABSTRACT mRNA encapsulated in lipid nanoparticles (LNPs) provides a dual revolution in the field of gene therapy. mRNA brings fleeting efficacy and the possibility to adjust the therapy to clinical needs. LNP, as a non‐viral vehicle with flexible organ‐targeting, overcomes most immune complications of viral gene therapy. mRNA‐LNP has rapidly progressed
Sonam Gurung +4 more
wiley +1 more source
5'-nucleotidases, nucleosides and their distribution in the brain: pathological and therapeutic implications [PDF]
, 2013 Elements of the nucleoside system (nucleoside levels, 5'-nucleotidases (5'NTs) and other nucleoside metabolic enzymes, nucleoside transporters and nucleoside receptors) are unevenly distributed in the brain, suggesting that nucleosides have region ...
Dobolyi, Árpád +3 more
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Modification of guanine nucleotide-regulatory components in brain membranes. II. Relationship of guanosine 5'-triphosphate effects on opiate receptor binding and coupling receptors with adenylate cyclase [PDF]
, 1984 SR Childers, G R Lariviere
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Heavy Metals Toxicity: Mechanism, Health Effects, and Therapeutic Interventions
MedComm, Volume 6, Issue 9, September 2025.Heavy metals exert a wide range of effects at the cellular, molecular, and genetic levels, leading to neurological damage, renal dysfunction, cardiovascular disease, reproductive developmental abnormality, immune system abnormality, and increased risk of cancer by interfering with biomolecule function, signaling pathways, inducing oxidative stress, and
Yu‐feng Cheng +3 more
wiley +1 more source
Activation of phospholipase C associated with isolated rabbit platelet membranes by guanosine 5′-[γ-thio]triphosphate and by thrombin in the presence of GTP [PDF]
, 1987 Janet K. Hrbolich +2 more
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