Revisiting the microtubule based quantum models of mind: tubulin bound GTP cannot pump microtubule coherence or provide energy for alpha <-> beta computation in stable microtubules [PDF]
The current paper investigates the biological models of stable brain microtubules as quantum or classical computers whose function is based on electron hopping associated with kinking of the tubulin dimer. Hameroff (1998a, 1998b, 2003a, 2003b), Tuszynski
Georgiev, Danko
core
IgM Antibodies Can Access Cryptic Antigens Denied to IgG: Hypothesis on Novel Binding Mechanism
Antibodies are well-known protein mediators of immunity. IgM is the primordial member and the neglected sibling of the later-evolved and more proficient IgG in regard to their therapeutic and diagnostic use.
Eric Chun Yiu Law+7 more
doaj +1 more source
The Utilization of Purines and Their Ribosyl Derivatives for the Formation of Adenosine Triphosphate and Guanosine Triphosphate in the Rabbit Reticulocyte [PDF]
Abstract The rabbit reticulocyte is capable of utilizing purines and their ribosyl derivatives for nucleoside triphosphate formation. Adenine, adenosine, hypoxanthine, and inosine are used extensively for the synthesis of adenosine triphosphate. Xanthine, guanine, and guanosine are utilized primarily for the synthesis of guanosine triphosphate.
Jean L. Cook, Madeleine Vibert
openaire +2 more sources
Control of Nucleotide Metabolism and Ribosomal Ribonucleic Acid Synthesis During Nitrogen Starvation of \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]
Ribosomal ribonucleic acid (RNA) synthesis and ribonucleoside triphosphate metabolism were studied in cultures of Escherichia coli subjected to starvation for inorganic nitrogen.
Irr, Joseph D.
core +1 more source
The synthesis of guanosine 5'-diphosphate D-glucose by enzyme extracts of mung beans (Phaseolus aureus) and other higher plants [PDF]
In response to a statement in the recent literature that the enzyme responsible for the synthesis of guanosine 5'-diphosphate D-glucose had been found only in pea seeds, enzyme extracts were prepared from a variety of higher plants.
Barber, G.A.
core +1 more source
Aims Shunting (hypermethylating) thiopurine metabolism, characterized by excessive 6‐MMPR production and (sub)therapeutic 6‐TGN levels, poses a significant challenge in the treatment of inflammatory bowel disease (IBD). This study evaluates the metabolic outcomes of switching to low‐dose thiopurine with allopurinol (LDTA) or thioguanine (TG) in IBD ...
Ahmed B. Bayoumy+4 more
wiley +1 more source
Zr(IV) can form phosphate and Zr(IV) (–PO32−–Zr4+–) complex owing to the high affinity between Zr(IV) with phosphate. Zr(IV) can induce the aggregation of gold nanoparticles (AuNPs), while adenosine triphosphate(ATP) can prevent Zr(IV)-induced ...
Wenjing Qi+4 more
doaj +1 more source
Fermentation of xylose causes inefficient metabolic state due to carbon/energy starvation and reduced glycolytic flux in recombinant industrial Saccharomyces cerevisiae. [PDF]
In the present study, comprehensive, quantitative metabolome analysis was carried out on the recombinant glucose/xylose-cofermenting S. cerevisiae strain MA-R4 during fermentation with different carbon sources, including glucose, xylose, or glucose ...
Akinori Matsushika+3 more
doaj +1 more source
Metabolic Engineering of Bacillus subtilis for Riboflavin Production: A Review
Riboflavin (vitamin B2) is one of the essential vitamins that the human body needs to maintain normal metabolism. Its biosynthesis has become one of the successful models for gradual replacement of traditional chemical production routes. B.
Yang Liu+6 more
doaj +1 more source
Targeting KRAS in Cancer Therapy: Beyond Inhibitors. [PDF]
MedComm, Volume 6, Issue 7, July 2025.
Chen C, Peng Z, Zhang L.
europepmc +2 more sources