Results 21 to 30 of about 3,853 (75)
Physiological Reports, Volume 13, Issue 22, November 2025.CORM‐A1 delivers carbon monoxide (CO) to the kidney and improves renal function following warm ischemia‐reperfusion (I/R) in rats and pigs. Abstract Carbon monoxide (CO), a gas endogenously produced in mammalian tissues, exerts vasodilatory, anti‐ischemic, and anti‐inflammatory effects.
Roberta Foresti +5 more
wiley +1 more source
Advanced Science, Volume 12, Issue 37, October 6, 2025.NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu +15 more
wiley +1 more source
Advanced Science, Volume 12, Issue 38, October 13, 2025.The novel microneedle patches (MN@CTB) are fabricated by integrating CTB nanozymes into HAMA and PVA solution based on a photo‐crosslinking reaction. The MN@CTB microneedle patches present an excellent photothermal effect and NIR‐stimulated release of NO, which is advantageous for the elimination of MRS.
Wei Qian +13 more
wiley +1 more source
Developmental Neurobiology, Volume 85, Issue 4, October 2025.ABSTRACT Prenatal stress, mediated by elevated glucocorticoid (GC) levels, is a relevant modulator of fetal brain development and a known risk factor for neurodevelopmental disorders. Using the avian embryo as a vertebrate model, we injected corticosterone into the yolk on embryonic day 6 (E6) and assessed neurodevelopmental outcomes at day 14 (E14 ...
Bela Gaertner +9 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.ABSTRACT Metabolic syndrome (MS) is a multifaceted condition characterised by insulin resistance, dyslipidemia, central obesity and hypertension, significantly elevating the risks of cardiovascular diseases and type 2 diabetes. This review aims to elucidate the bidirectional interplay between anaesthetic agents and MS, highlighting the mutual influence
Yuying Huang +6 more
wiley +1 more source
Electrochemistry as a Tool for Redox‐Based Bio‐Information Processing
Advanced Science, Volume 12, Issue 36, September 25, 2025.Redox is a modality that is native to biology and accessible to electronics through electrochemistry. Imposed electronic inputs are transduced into redox signals that can probe for bio‐information or actuate biological responses. Measured electronic output responses are analyzed to reveal actionable information.
Eunkyoung Kim +8 more
wiley +1 more source
Increased contractility affects left ventricular kinetic energy in pulmonary hypertension
Physiological Reports, Volume 13, Issue 17, September 2025.Abstract Precapillary pulmonary hypertension (PH) is characterized by increased pulmonary vascular resistance (PVR), with progressively altered right (RV) and left ventricular (LV) hemodynamics and function. Kinetic energy (KE) from 4D flow cardiovascular magnetic resonance (CMR) is a measure of intracardiac hemodynamics.
E. Bergström +8 more
wiley +1 more source
Physiological Reports, Volume 13, Issue 16, August 2025.Aerobic exercise attenuates obesity‐induced tPVAT dysfunction by reducing inflammation, oxidative stress, and restoring anti‐contractile vascular response in female mice. Abstract The goal of the study was to investigate the effects of aerobic exercise training on inflammatory, oxidative stress, and cellular senescence biomarkers, along with the ...
Teresa M. Da‐Re +5 more
wiley +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 7, July 2025.This systematic review and meta‐analysis evaluated the therapeutic efficacy of Astragaloside IV in ischemic heart disease, encompassing 18 preclinical studies. The findings demonstrated that As‐IV significantly reduced myocardial infarction size and apoptosis while improving cardiac function and angiogenesis through various mechanisms, along with ...
Alosh Greeny +7 more
wiley +1 more source