Results 81 to 90 of about 102,937 (395)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Intentions and Results: A Look Back at the Adoption and Safe Families Act [PDF]
Compiles papers and policy briefs examining the intended and unintended consequences for children, families, and the child welfare system of the 1997 law to prioritize child safety in case decision making and connect children to permanent ...
Jennifer Macomber +3 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
THE PURPOSE OF LAW, PANCASILA AND LEGALITY ACCORDING TO ERNST UTRECHT: A CRITICAL REFLECTION
Ernst Utrecht is one of the best legal scholars Indonesia has ever had. His political views position him as an organic intellectual; a legal scholar involved in and expressing the social consciousness, both in the academic as well as in the political ...
Fernando Morganda Manullang
doaj +1 more source
Notice and Intervention in ICWA CINA Cases 1992 [PDF]
This study is a preliminary investigation of the relationship between the notice requirement and intervention in a sample of Indian Child Welfare Act (ICWA) Child in Need of Aid (CINA) cases in Alaska in 1992.
Rieger, Lisa
core
This study examines the socio-economic factors influencing public awareness of the adult guardianship and civil trust systems in Japan. The results of this study show that financial literacy is the most influential factor affecting knowledge of the adult
Yoshihiko Kadoya +3 more
semanticscholar +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Context and relevance. The human world is characterized by a special aspect of assessing obligation, acceptability, desirability. The deontic nature of the social situation of personality development is complicated by the diversity of its ...
N.V. Lukyanchenko +2 more
doaj +1 more source
Uzbekistan Supplementary NGO Report on the Implementation of the Convention on the Rights of the Child in the Republic of Uzbekistan [PDF]
[Excerpt] The Convention on the Rights of the Child (CRC) was one of the first international instruments to which the Republic of Uzbekistan acceded, and with parliamentary ratification on 9 December 1992, the Republic of Uzbekistan entered into a ...
core +1 more source

