Results 111 to 120 of about 5,911,359 (363)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases

Hepatology, 2018
Author(s): Marrero, Jorge A; Kulik, Laura M; Sirlin, Claude B; Zhu, Andrew X; Finn, Richard S; Abecassis, Michael M; Roberts, Lewis R; Heimbach, Julie ...
Jorge A. Marrero, Laura M. Kulik, C. Sirlin, Andrew X. Zhu, R. Finn, Michael M Abecassis, Lewis R. Roberts, J. Heimbach   +7 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Enhancing counseling teachers’ creativity through Deep Counseling-based Training

Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang
This community service program aimed to enhance the creativity of guidance and counseling teachers through deep counseling-based training. The training was conducted on July 10, 2025, involving 49 guidance and counseling teachers from junior and senior ...
Eka Sakti Yudha, Ahman, Agus Taufiq, Dian Munawarah, Kania Cahyaningtyas, Moch. Dendi Arief Prawira, Muzayyinah Al-Usrah, Yalda Suvita   +7 more
doaj   +1 more source

AASLD practice guidance on the clinical assessment and management of nonalcoholic fatty liver disease.

Hepatology, 2023
M. Rinella, B. Neuschwander‐Tetri, M. Siddiqui, M. Abdelmalek, S. Caldwell, D. Barb, D. Kleiner, R. Loomba   +7 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Impact of a mobile career counseling app on career decision-making self-efficacy in students’ transition to higher education

Discover Psychology
Final-year high school students continue to face challenges in transitioning to higher education, with limited time to make crucial career decisions.
Lolang Maria Masi, I Putu Agus Apriliana, Khetye Romelya Saba, Zummy Anselmus Dami   +3 more
doaj   +1 more source

Optimizing Aircraft Turnaround Operations Through Intelligent Technology Integration: A Comprehensive Analysis of the INTACT System’s Impact on Flight Efficiency and Economic Performance

Aerospace
Delays during turnaround operations are a significant source of operational inefficiency for airlines. They reduce airline profit margins by resulting in rescheduled flights and missed connections for passengers. This research paper presents the findings
Parth Yogeshbhai Purohit, Jonas Ernst Bernhard Langner, Thomas Feuerle, Peter Hecker   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source