Results 131 to 140 of about 1,187,762 (269)
Minimum-Excess-Work Guidance: Score-Based Sampling with Experimental Data or Sparse Restraints. [PDF]
Kolloff C +6 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Indirect Effect of Maltreatment on Child Cooperation and Exploration Through Maternal Sensitive Guidance. [PDF]
Boulus JM, Edler K, Valentino K.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Evaluating the Pediatric Behavior Guidance of Students Based on Actual Clinical Transcripts Scored by Faculty and Large Language Models: Pilot Comparative Study. [PDF]
Dhillon IK, Lee GKY, Hu S.
europepmc +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
The Guidance of Verbal Working Memory Content to Attention. [PDF]
Duan C, Song D, Yuan L, Zhang L.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Analysis of advice and guidance primary care queries to rheumatology over a calendar year-a diagnostic service evaluation. [PDF]
O'Shaughnessy E, Mulhearn B, Bukhari M.
europepmc +1 more source

