Results 111 to 120 of about 105,034 (263)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

School Counselors’ Meaning in Life as a Foundation for Professional Well-being and Professionalism: A Phenomenological Study

Bisma The Journal of Counseling
The complex and demanding role of school counselors requires a strong sense of meaning in life (MIL). MIL plays a vital role in helping counselors manage stress, maintain psychological well-being, and strengthen their professional identity.
Arni Nur Laila, Nur Mega Aris Saputra, Nur Asiah   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The Effectiveness of Cognitive Behavioral Group Counseling in Reducing Fear of Missing Out (FOMO) Among Vocational High School Students

Bisma The Journal of Counseling
Excessive dependence on social media among adolescents often triggers social anxiety, namely the phenomenon of Fear of Missing Out (FOMO). This condition creates emotional pressure due to the fear of missing out on information or digital trends, which ...
Agus Rizal Agus, Wisnu Kurniawan Wisnu, Amanatul Qudsiyah Ana   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Academic Hardiness Level of Guidance and Counseling Study Program Students Post Covid 19 Pandemic [PDF]

The purpose of this study is to inform the condition of Academic hardiness of Ahmad Dahlan University Guidance and Counseling Study Program students after the Covid-19 pandemic.
Rifqoh, Fany, Setyowati, Aprilia, Astuti, Budi, Fauziah, Mufied, Farozin, Muh   +4 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

The Problem of Misconceptions about Guidance and Counseling Globally

Counseling is a service provided by professional staff to individuals or groups for the development of effective daily living. However, the phenomenon that occurs in the field is that the implementation of Guidance and Counseling in schools is carried ...
Zahri, Triave Nuzila, Triyono, Triyono, Febriani, Rahmi Dwi, Sari, Azmatul Khairiah, Handayani, Puji Gusri   +4 more
core   +1 more source