Results 101 to 110 of about 105,034 (263)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Acculturation and inter-ethnic attitudes [PDF]
, 1976 The Emergency School Aid Act (ESAA) provided funds for cultural education programs in Hawaii's public schools, with the goal of improving intercultural and interpersonal relations.
Okumura, Yoko
core +1 more source
Bisma The Journal of CounselingSexual harassment can have long-term negative effects on victims, one of which is a decrease in self-compassion. A decline in self-compassion may hinder the achievement of individuals’ developmental tasks. This study aims to analyze the effectiveness of
Rizka Apriani +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Hopelessness and Helplessness Scale: Validity and measurement invariance
Journal of Happiness and HealthThis study set out to investigate the psychometric properties of the Hopelessness and Helplessness Scale (HHS), which was designed to measure an individual’s levels of hopelessness and helplessness.
Erdinç Duru, Murat Balkis, Sibel Duru
doaj +1 more source
Attitude scale towards LGBTI individuals: Validity and reliability study [PDF]
Journal of Pedagogical Research, 2017 The purpose of this study was to develop an instrument to measure university students’ attitudes towards LGBTI individuals. The sample included 220 university students attended a public university located in the west of Turkey during 2016-2017 education ...
Kübra Çiçek +2 more
doaj
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Jurnal Ilmiah Bimbingan Konseling UndikshaThe learning process of students is influenced by both internal and external factors, including academic anxiety arising from cognitive distortions. This anxiety can disrupt concentration, lower academic performance, and trigger maladaptive behaviors ...
I Gusti Ayu Anggita Nada Dewi +2 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Development of a Psychological Well-Being Instrument in Secondary Schools
Bisma The Journal of CounselingPsychological well-being is a crucial psychological condition that every individual should possess, as a high level of psychological well-being contributes significantly to the overall course of a person’s life. The purpose of this study is to develop a
Romi Fajar Tanjung +5 more
doaj +1 more source