Results 121 to 130 of about 105,034 (263)

An investigation into the development of pre-service teachers in a guidance training programme and its implications for their guidance role in schools [PDF]

open access: yes, 2002
This study investigates the development of pre-service teachers with reference to the core conditions of counselling in a guidance training programme, which is a part of a pre-service new B.Ed, module.
Lung, Jacob C. L.
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Çocuk ve Ergenlerde Siber Zorbalıkla Başa Çıkmada Gerçeklik Terapisinin Etkililiğinin İncelenmesi

open access: yes, 2019
In recent years, the developments in the Internet and communication technologies have led to new additional problems that are faced by children and adolescents.
Uygarer, Gülen
core  

Adapting the celebrity attitude scale: A validity and reliability study in a Turkish sample

open access: yes
The Celebrity Attitude Scale (CAS; McCutcheon et al., 2004) measures attitudes toward celebrities across three dimensions: entertainment-social, intense-personal, and mild pathology.
Arı, E.   +3 more
core   +1 more source

Intern and non-intern school counselor's perceived level of effectiveness on counselor job functions [PDF]

open access: yes, 2001
Plan BThe question of whether school counselors with teaching experience are more effective in performing counseling job functions as compared to counselors without teaching experience has been relatively ignored in the last two decades.
Vavricka, Rochelle Lynn
core  

Research Trends of Suicidal Ideation in College Students: Causal Factors and Intervention

open access: yesBisma The Journal of Counseling
Suicidal ideation among university students has become a significant global mental health issue. Academic, social, and economic pressures increase students’ vulnerability to suicidal thoughts.
Abi Fa'izzarahman Prabawa   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Parents' perceptions of the role and function of a high school guidance counselor [PDF]

open access: yes, 2003
Plan BParents play an integral role in their child’s education and are perhaps the most important link between the home and school. Therefore, if a counselor understands parents’ perceptions of the role and function of the high school counselor, the ...
Quast, Courtney
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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