Results 81 to 90 of about 73,176 (262)

The Effectiveness of Cognitive Behavioral Counseling Using Cognitive Restructuring Techniques in a Group Counseling Setting to Address Academic Anxiety in Vocational High School Students

Jurnal Ilmiah Bimbingan Konseling Undiksha
The learning process of students is influenced by both internal and external factors, including academic anxiety arising from cognitive distortions. This anxiety can disrupt concentration, lower academic performance, and trigger maladaptive behaviors ...
I Gusti Ayu Anggita Nada Dewi, Dewi Arum Widhianti Metra Putri, Luh Putu Sri Lestari   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The Effectiveness of Cognitive Behavioral Group Counseling in Reducing Fear of Missing Out (FOMO) Among Vocational High School Students

Bisma The Journal of Counseling
Excessive dependence on social media among adolescents often triggers social anxiety, namely the phenomenon of Fear of Missing Out (FOMO). This condition creates emotional pressure due to the fear of missing out on information or digital trends, which ...
Agus Rizal Agus, Wisnu Kurniawan Wisnu, Amanatul Qudsiyah Ana   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Development of a Psychological Well-Being Instrument in Secondary Schools

Bisma The Journal of Counseling
Psychological well-being is a crucial psychological condition that every individual should possess, as a high level of psychological well-being contributes significantly to the overall course of a person’s life. The purpose of this study is to develop a
Romi Fajar Tanjung, Sigit Dwi Sucipto, Yola Eka Putri, Abelia Agustin, Citra Finky Lestary, Nabila   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Implementation of Guidance and Counseling Teacher Competencies in the Actuating of Guidance and Counseling in Schools

JMKSP (Jurnal Manajemen, Kepemimpinan, dan Supervisi Pendidikan)
Guidance and counseling teachers have a crucial role in helping students overcome various personal, social, and academic problems and optimally develop their potential. By having appropriate competencies, guidance, and counseling teachers can provide services that are more effective and relevant to student needs, thereby improving overall student ...
Naila Rumaisha Aqra, Uman Suherman AS
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

School Counselors’ Meaning in Life as a Foundation for Professional Well-being and Professionalism: A Phenomenological Study

Bisma The Journal of Counseling
The complex and demanding role of school counselors requires a strong sense of meaning in life (MIL). MIL plays a vital role in helping counselors manage stress, maintain psychological well-being, and strengthen their professional identity.
Arni Nur Laila, Nur Mega Aris Saputra, Nur Asiah   +2 more
doaj   +1 more source