Results 71 to 80 of about 105,034 (263)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Guidance and counseling in Hong Kong secondary schools.
, 2014 This article provides a description of the current status of guidance and counseling in secondary schools in HongKong, and identifies some of the strengths and weaknesses in existing provisions.
Chan, RTH, Lee, BSF, Yuen, MT
core +1 more source
Self-esteem, Social Support, Personality and Psychological Well Being of Junior High School Student
Jurnal Pendidikan Humaniora, 2018 : The aims of this study was to understand how the relationship between self-esteem, social support, extraversion personality, agreeableness personality, conscientiousness personality, neuroticism personality, openness personality, and psychological well-
Mufied Fauziah +2 more
doaj
Journal of EST (Educational Science And Technology). Adolescents face increasing family and academic demands that may compromise their psychological well-being and sense of meaning in life. Father-love absence has been identified as a significant psychological risk factor undermining adolescents' well ...
Mufied Fauziah +4 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Evaluating career self-awareness instruments for victims of violence using the Rasch model
BMC PsychologyBackground Victims of violence have trauma that often affects career development. A tool is needed to measure a person’s self-perception of self and work environment.
Mamat Supriatna +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Jurnal Ilmiah Bimbingan Konseling UndikshaCommunication and public speaking skills are essential for counselors to establish effective therapeutic relationships. However, communication barriers often reduce the quality of counseling. This study aims to analyze the effectiveness of Problem-Based
Azba Novanda Fasha +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source