Results 131 to 140 of about 553,709 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Building the lac Operon: A Guided-Inquiry Activity Using 3D-Printed Models. [PDF]

open access: yesJ Microbiol Biol Educ, 2020
Gordy CL   +4 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Pembelajaran Berbasis Guided Inquiry untuk Meningkatkan Literasi Sains Siswa Kelas X MIPA pada Materi Larutan Elektrolit dan Nonelektrolit [PDF]

open access: yes, 2019
Penelitian ini bertujuan untuk menganalisis kemampuan literasi sains siswa kelas X program IPA melalui model pembelajaran inkuiri terbimbing (guided inquiry) pada materi larutan elektrolit dan non elektrolit, efektivitas pembelajaran dan peningkatan ...
Yessi, M. (Miokti)
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

PENGARUH MODEL GUIDED INQUIRY TERHADAP KETERAMPILAN PROSES DAN HASIL BELAJAR ASPEK KOGNITIF DALAM PELAJARAN IPA SMP KELAS VII DENGAN TEMA PEMANASAN GLOBAL [PDF]

open access: yes, 2015
Penelitian ini bertujuan untuk mengetahui: (1) pengaruh model guided inquiry terhadap keterampilan proses siswa dalam pembelajaran IPA SMP kelas VII dengan “tema pemanasan global”, (2) pengaruh model guided inquiry terhadap hasil belajar aspek kognitif
Nursalis, Dede Yanti
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

PENGEMBANGAN PERANGKAT PEMBELAJARAN FISIKA BERBASIS GUIDED INQUIRY UNTUK MENGEMBANGKAN KETERAMPILAN BERPIKIR KRITIS PESERTA DIDIK MAN YOGYAKARTA III [PDF]

open access: yes, 2015
Penelitian ini bertujuan untuk mengetahui: (1)Kelayakan perangkat pembelajaran fisika berbasis guided inquiry untuk membelajarkan peserta didik sehingga mampu mencapai keterampilan berpikir kritis di MAN Yogyakarta III.
Windiarti, Desinta
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Using PhET simulation as guided inquiry-assisted virtual biology laboratory to enhance science literacy skills of junior high school students in West Lampung

open access: yesAssimilation
This study aims to determine the effect of implementing a guided inquiry model with assistance PhET simulation as virtual laboratory towards improving students' scientific literacy skills.
Median Agus Priadi   +2 more
doaj   +1 more source

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