Results 121 to 130 of about 1,156,699 (297)
The Effect of Guided Inquiry Learning Method VS Free Inquiry Against Learning Outcomes [PDF]
, 2017 This research is motivated by the lack of use of various methods in learning the basics of accounting which resulted in low student results. Issues that will be examined in this study is whether there are differences in student learning outcomes using ...
Setyosari, Punaji +3 more
core
A pedagogical exploration of guided reading in three primary classrooms
, 2013 The focus of this study is what Alexander (2000) refers to as the ‘heart of pedagogy’: the moment-by-moment transactions between a teacher and a small group of learners, viewed through a socio-cultural lens.
Challen, Doreen
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Building the lac Operon: A Guided-Inquiry Activity Using 3D-Printed Models. [PDF]
J Microbiol Biol Educ, 2020 Gordy CL +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
NUMBERED HEADS TOGETHER DIPADU INKUIRI TERBIMBING MELALUI LEASSON STUDY PADA PEMBELAJARAN BIOLOGI
, 2014 : The learning Biology in SMA 1 Batu indicates that student have low motivation because teacher centers learning and the tendency to do worksheets individualy in every meeting.
dan Siti Imroatul Maslikah, Henyta Agustina, Sri Endah Indriwati,
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source