Results 101 to 110 of about 1,156,699 (297)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Introducing Guided Mathematical Inquiry in the classroom: complexities of developing norms of evidence

open access: yes, 2019
Guided Mathematical Inquiry (GMI) supports the development of deep understandings about mathematics concepts as students learn to address inquiry questions with evidence-based claims.
Fry, Kym, Fielding-Wells, Jill
core  

The Effect of the Guided Inquiry Learning Model on Critical Thinking Skills in Science Education: A Systematic Literature Review

open access: yesThinking Skills and Creativity Journal
Students’ critical thinking skills in science learning remain underdeveloped due to teacher-centered instructional practices that limit active engagement in inquiry and reasoning. This study aims to analyze empirical evidence on the effect of the guided
Luh Ririn Indahyani   +4 more
doaj   +1 more source

PEMBELAJARAN KIMIA MENGGUNAKAN METODE EKSPERIMEN DAN GUIDED INQUIRY DITINJAU DARI KEMAMPUAN MATEMATIS DAN KREATIVITAS SISWA

open access: yesInkuiri, 2014
Tujuan penelitian ini adalah untuk mengetahui pengaruh pembelajaran kimia dengan menggunakan metode eksperimen dan guided inquiry, kemampuan matematis, kreativitas, dan interaksinya terhadap prestasi belajar siswa.Penelitian ini merupakan penelitian ...
Atik Puji Rahayu   +2 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Philosophical Inquiry to Advance Cosmopolitan Engagement

open access: yes, 2012
Il progetto intende promuovere lo sviluppo di attitudini, competenze, stili di pensiero caratterizzati dalla capacità di essere riflessivamente consapevoli delle proprie radici e della propria identità e allo stesso tempo di aprirsi al nuovo e al ...
Camhy D.   +3 more
core  

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