Results 91 to 100 of about 1,156,699 (297)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Introductory Chemistry: A Guided Inquiry 2nd Edition

open access: yes, 2015
The ChemActivities found in Introductory Chemistry:A Guided Inquiry use the classroom guided inquiry approach and provide an excellent accompaniment to any one semester Introductory text.
Garoutte, Michael P, Mahoney, Ashley B
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

UPAYA MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS DENGAN STRATEGI INKUIRI TERBIMBING

open access: yes, 2014
: This research aims to improve critical thinking skills and student learning outcomes through the implementation of the Integrated Science teaching materials with guided inquiry learning strategies at  VII class SMPN I Singosari.
dan Sulisetijono, Nana Maria Ulfa
core  

PENGARUH MODEL PEMBELAJARAN OPEN INQUIRY DAN GUIDED INQUIRY TERHADAP SIKAP ILMIAH SISWA SMP PADA TEMA SUHU DAN PERUBAHAN

open access: yesEDUSAINS, 2016
Tujuan penelitian ini adalah untuk menganalisis perbedaan sikap ilmiah antara siswa yang menggunakan model pembelajaran Open Inquiry dengan siswa yang menggunakan model pembelajaran Guided Inquiry pada tema suhu dan perubahan.
Dwi Indah Suryani, Dwi Indah Suryani
doaj   +1 more source

A gut microbiome tactile teaching tool and guided-inquiry activity promotes student learning. [PDF]

open access: yesFront Microbiol, 2022
Shoaf PT   +4 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Implementation of Pedagogical Content Knowledge (PCK) based Guided Inquiry on Science Teacher Students

open access: yesJurnal Penelitian dan Pembelajaran IPA, 2018
The aim of this study is examining the learning of Integrated Sciences through PCK based guided inquiry on prospective science teacher students. This research method was descriptive qualitative involving 33 science teacher students who taking Integrated ...
Lulu Tunjung Biru   +4 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

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