Results 51 to 60 of about 31,758 (264)
Guided Inquiry Lessons For Introduction To Materials [PDF]
Comment: 12 ...
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In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Guided inquiry of genomics in NMPDR
Bioinformatics has become an indispensable tool in the arsenal of biochemists and molecular biologists. Most of today's experimental research relies on in silico analytical tools for making sense of the gathered data, making predictions, and formulating working hypotheses.
Leslie Klis McNeil, Claudia Reich
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Guided Inquiry Method Employing Virtual Laboratory to Improve Scientific Working Skills
: There are many obstacles in achieving the goals of learning physics. One of those is how students’ assumption on physics as something abstract and can not be verified by experiment, because of the unavailability of laboratory and equipment in schools ...
Siti Juwariyah +2 more
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Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
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Pengaruh Integrative Learning Terhadap Kemampuan Berpikir Kritis dan Penguasaan Konsep Fisika Siswa
: This research aimed to examine influence of integrative learning and guided inqury learning on concept achievement and critical thinking of students. This research used a quasi-experimental with posttest only control group design.
Lis Suswati, Lia Yuliati, Nandang Mufti
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

