Results 91 to 100 of about 37,653 (258)

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Coaxial electrospinning of poly(ɛ-caprolactone)/gelatin core-shell biodegradable implants for localized delivery of metronidazole and dexamethasone for periodontal applications

Frontiers in Bioengineering and Biotechnology
IntroductionCore-shell electrospun scaffolds may help coordinate antibacterial and immunomodulatory effects during periodontal healing. Their unique architecture may enable a more spatiotemporal control over the delivery of therapeutic agents. This study
Sarah Chang, Caroline Anselmi, Caroline Anselmi, Igor Mendes Soares, Igor Mendes Soares, Lais Medeiros Cardoso, Lais Medeiros Cardoso, Alexandre Henrique dos Reis-Prado, Alexandre Henrique dos Reis-Prado, Ana Beatriz Gomes de Carvalho, Ana Beatriz Gomes de Carvalho, J. Christopher Fenno, Renan Dal-Fabbro, Josimeri Hebling, Josimeri Hebling, Marco C. Bottino, Marco C. Bottino   +16 more
doaj   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Simultaneous Electrochemical Detection of NGF and proNGF Under Native Conditions Using Molecularly Imprinted Polymers: Toward Point‐of‐Care Diagnosis of Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
This study relies on the development of a new sensor that can detect two closely related proteins involved in Alzheimer's disease at the same time. Unlike traditional methods, it works in natural conditions and does not require sample pretreatment. The device is highly sensitive and was successfully tested on patient samples, offering promises for ...
Giulia Siciliano, Alfredo De Cillis, Elena Clabassi, Francesco Ferrara, Maria Serena Chiriacò, Antonio Turco, Clarissa Loiola, Chiara Zecca, Maria Teresa Dell'Abate, Giancarlo Logroscino, Giuseppe Gigli, Francesca Malerba, Elisabetta Primiceri   +12 more
wiley   +1 more source

Recent Advances in Regenerative Therapies in Periodontology

Dentistry Journal
Background/Objectives: Periodontal regeneration remains a primary goal in contemporary periodontal therapy, aiming to restore both the structural and functional integrity of tissues lost due to periodontitis.
Andrei-Mario Bădărău-Șuster, Edwin Sever Bechir, Zsuzsanna Bardocz-Veres, Ana Petra Lazăr, Alexandru Vlasa, Mircea Suciu, Tatiana-Maria Coman, Luminița Lazăr   +7 more
doaj   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Seta‐Inspired Mechano‐Intelligent Janus Bandage with Coordinated Adhesion–Contraction for Minimizing Scarring

Advanced Materials, EarlyView.
We developed a bioinspired mechano‐intelligent Janus bandage (MIB) with a hydrophobic flat exterior and a hydrophilic interior featuring gecko‐mimicking wedged microstructures, fabricated via micromolding and anisotropic plasma treatment. The MIB dynamically synchronizes adhesion and contraction, enabling precise force modulation.
Di Suo, Yuhe Yang, Shuai Zhao, Ho‐Pan Bei, Avery Chik‐Him Lam, Wei‐Qiang Tan, Kenneth Kak‐yuen Wong, Xin Zhao   +7 more
wiley   +1 more source

E7-Conjugated Bio-Inspired Microspheres as a Biological Barrier for Guided Tissue Regeneration. [PDF]

ACS Appl Mater Interfaces, 2023
Hu Z, Rong X, Liu X.
europepmc   +1 more source