Results 71 to 80 of about 16,189,469 (293)

Integrating guideline development and implementation: analysis of guideline development manual instructions for generating implementation advice

open access: yesImplementation Science, 2012
Background Guidelines are important tools that inform healthcare delivery based on best available research evidence. Guideline use is in part based on quality of the guidelines, which includes advice for implementation and has been shown to vary.
Gagliardi Anna R, Brouwers Melissa C
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Deciding to Enrol in a Cancer Trial: A Systematic Review of Qualitative Studies

open access: yesJournal of Multidisciplinary Healthcare, 2020
Bianca Viljoen,1– 3 Suzanne K Chambers,1,2,4– 7 Jeff Dunn,1,2,4,5 Nicholas Ralph,1,3– 5 Sonja March1,8 1Centre for Health Research, Institute for Resilient Regions, University of Southern Queensland, Springfield, Brisbane, Australia ...
Viljoen B   +4 more
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Guideline development tasks, their weight scores, and their coverage in the guideline development handbooks.

open access: yes, 2013
Guideline development tasks, their weight scores, and their coverage in the guideline development handbooks.
Shabnam Ansari (297405)   +1 more
core   +1 more source

THE DEVELOPMENT AND MEANING OF APPROPRIATENESS GUIDELINES

open access: yesRadiologic Clinics of North America, 1995
Practice guidelines are important for high quality and economical patient care. As gatekeepers to health care, primary care physicians should refer to imaging guidelines when treating a patient with breast disease. The American College of Radiology (ACR) has undertaken the task of publishing guidelines for breast imaging in the hopes of avoiding a ...
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Irish oral health services guideline initiative. Oral health assessment: Best practice guidance for providing an oral health assessment programme for school-aged children in Ireland. 2012 [PDF]

open access: yes, 2012
In the Republic of Ireland, the Health Service Executive (HSE), which is the national authority responsible for health and personal social services, has statutory responsibility to make dental services available, free of charge, to children under the ...
Guideline Development Group
core  

Stop Smoking: National Clinical Guideline No. 28

open access: yes, 2022
This National Clinical Guideline has been developed by the Stop Smoking Guideline Development Group (GDG), within the Tobacco Free Ireland Programme, Strategy & Research, Healthcare Strategy, Health Service Executive (HSE).
Department of Health (DoH)   +1 more
core  

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