Results 141 to 150 of about 2,950,340 (242)

Building Your Best Day: Disseminating the Canadian 24-Hour Movement Guidelines for Children and Youth via an Interactive Website. [PDF]

Child Care Health Dev
Gierc M, Walters A, Tennant EM, Tremblay MS, Faulkner G, Latimer-Cheung A.   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Reflecting on Reporting Guidelines in Qualitative Inquiry: Advocating for Openness or Methodological Specificity in Constructivist Grounded Theory. [PDF]

Glob Qual Nurs Res
Bobbink P, Larkin P, Probst S.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

AI Ethics Guidelines: Time to Include Animals. [PDF]

Sci Eng Ethics
Coghlan S, Parker C, Lederman R.
europepmc   +1 more source

Reporting Guidelines for the Early-Phase Clinical Evaluation of Applications Using Extended Reality: RATE-XR Qualitative Study Guideline

Johan H. Vlake, Denzel L. Q. Drop, Jasper van Bommel, Giuseppe Riva, Brenda K. Wiederhold, Pietro Cipresso, Albert Rizzo, Barbara O. Rothbaum, Cristina Botella, Lotty Hooft, O. Joseph Bienvenu, Christian Jung, Bart F. Geerts, Evert‐Jan Wils, Diederik Gommers, Michel E. van Genderen, RATE-XR Expert Group   +16 more
openalex   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Mapping a path forward: addressing disease burden, pathways and solutions in ANCA-associated vasculitis. [PDF]

Rheumatology (Oxford)
Hellmich B.
europepmc   +1 more source

P314 Barriers And Facilitators To The Implementation Of Clinical Practice Guidelines: A Survey Among Physicians In Specialized Care [PDF]

, 2013
Eva Reviriego, M Iruretagoyena, Andoni Arcelay, Gemma Villanueva   +3 more
openalex   +1 more source