Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
When Covering and Discovering Are at Odds: How the Logic of US Health Insurance Undercuts the Promise and Equity of Precision Medicine for People with Hereditary Cancer Risks. [PDF]
Mrig EH +6 more
europepmc +1 more source
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Mapping and Quality Appraisal of Artificial Intelligence Preferential Reporting Checklists, Items, Guidelines, and Consensus in Healthcare: An Altmetric, Bibliometric, and Systematic Review. [PDF]
Vinay V +5 more
europepmc +1 more source
Recent initiatives on guidelines implementation: KT in primary care [PDF]
Louis‐Philippe Boulet
openalex +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
The Early Movers Clinician's Guide: Co-Designing a Resource for the 24-Hour Movement Guidelines in Paediatric Occupational Therapy. [PDF]
Taylor LG +4 more
europepmc +1 more source
The next frontier in critical care guidelines: rapid and trustworthy recommendations [PDF]
Reed Siemieniuk, Gordon Guyatt
openalex +1 more source

