Results 111 to 120 of about 1,513,604 (271)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
FUN3D and USM3D Analysis of the Propulsion Aerodynamic Workshop 2018 S-Duct Test Case [PDF]
This work presents the results of Fun3D and USM3D analyses that were performed for the 4th AIAA Propulsion Aerodynamics Workshop (PAW). The PAW workshop is separated into three sections that focus on internal duct flows, nozzle flows and a special topic.
Bozeman, Michael D. +2 more
core +1 more source
CPWF publication policies and guidelines: Version 1.2 [PDF]
, 2011 The Challenge Program on Water and Food (CPWF) was launched in 2002 as a reform initiative of the Consultative Group on International Agricultural Research (CGIAR).
Bayot, Ruvicyn S. +2 more
core
EVALUATION OF TEACHING MATERIALS OF EVALUATION OF LEARNING COURSES FOR PRIMARY SCHOOL TEACHERS EDUCATION STUDY PROGRAM OF UNIVERSITAS KATOLIK MUSI CHARITAS [PDF]
, 2020 This study aims to determine the needs of teaching materials for evaluasipembelajaran courses that support the ability of students to carry out assessment of learning outcomes in accordance with the development of current assesments in Education for ...
Indriasari, Bernadine Ajeng
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
A Ward-by-Ward Approach to Eliminating Open Defecation: Experience from Visakhapatnam, India [PDF]
, 2017 The Government of India launched the Swachh Bharat Mission (SBM) in 2014 with the ambitious aim to ensure hygiene, waste management and sanitation across the nation by the 150th anniversary of Gandhi's birth in October 2019.
Akhilesh Gautam, Sam Drabble
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Towards Identifying and closing Gaps in Assurance of autonomous Road vehicleS - a collection of Technical Notes Part 1 [PDF]
, 2020 This report provides an introduction and overview of the Technical Topic Notes (TTNs) produced in the Towards Identifying and closing Gaps in Assurance of autonomous Road vehicleS (Tigars) project.
Bloomfield, R. E. +10 more
core +3 more sources