Results 91 to 100 of about 1,528,496 (317)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Guide-based interventions aimed at reducing physical restraints in intensive care unit: a systematic review and meta-analysis of randomized controlled trials

open access: yesFrontiers in Medicine
ObjectiveDespite widespread advocacy and organizational support for reducing the utilization of physical restraint (PR) in clinical settings, its application remains prevalent on a global scale.
Yueli Ping   +11 more
doaj   +1 more source

MedlinePlus??: The National Library of Medicine?? Brings Quality Information to Health Consumers [PDF]

open access: yes, 2004
The National Library of Medicine???s (NLM??) MedlinePlus?? is a high-quality gateway to consumer health information from NLM, the National Institutes of Health (NIH), and other authoritative organizations.
Backus, Joyce E.B.   +2 more
core  

Predicting Good Configurations for GitHub and Stack Overflow Topic Models

open access: yes, 2019
Software repositories contain large amounts of textual data, ranging from source code comments and issue descriptions to questions, answers, and comments on Stack Overflow.
Treude, Christoph, Wagner, Markus
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Guía de práctica clínica para la Profilaxis quirúrgica antimicrobiana

open access: yesInfectio, 2022
cal patient, as well as on the costs associated with health care. The adequate use of surgical antimicrobial prophylaxis being a fundamental aspect in reducing the risk of SSI, taking into account that the inappropriate or indiscriminate use of ...
Carlos Arturo Álvarez-Moreno
doaj   +1 more source

Standardization for Defence Procurement - European Handbook : CEN Workshop 10 [PDF]

open access: yes, 2005
The European Commission (EC), DG Enterprise, endeavours the competitiveness of the European Defence Industry. The plethora of (national) standards, more than 10.000, are recognised by the EC as a major constraint and cost driver.
Bresson, Alain   +23 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Postpartum period: study of guidelines for Primary Health Care [PDF]

open access: yesRevista Brasileira de Saúde Materno Infantil
Objectives: to identify convergences and divergences between the recommendations of the World Health Organization and those of the Ministry of Health for postpartum care in Primary Health Care.
Eliane Gomes dos Santos, Daphne Rattner
doaj   +1 more source

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