Results 71 to 80 of about 462,681 (313)

World Health Organization guideline development : an evaluation [PDF]

, 2013
Background Research in 2007 showed that World Health Organization (WHO) recommendations were largely based on expert opinion, rarely used systematic evidence-based methods, and did not follow the organization's own “Guidelines for Guidelines”.
Tamara Kredo, Helen Smith (19020), Isba Rachel, Zani, Babalwa, Rachel Isba, Sinclair David, Isba, Rachel, Kredo Tamara, Garner Paul, Smith, Helen, Sinclair, David, Tamara Kredo (417544), Rachel Isba (190771), Paul Garner (7861), Zani Babalwa, David Sinclair, David Sinclair (413930), Babalwa Zani (191675), Helen Smith, Smith Helen, Paul Garner, Kredo, Tamara, Garner, Paul, Babalwa Zani   +23 more
core   +1 more source

Adapting Clinical Guidelines for the Digital Age [PDF]

Clinical guidelines are systematically developed statements to assist practitioners and patients make decisions about health care based on the latest evidence. The long, narrative format of guidelines can make adherence difficult.

core   +2 more sources

Writing a Case Report: A Work of Art

International Journal of Medical Students, 2015
Case reports are a time-honored, important, integral, accepted part firmly established within the medical literature, and represent a growing importance of valuable clinical medical information.
Christian Ortega-Loubon, Ricardo Correa-Márquez   +1 more
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

CDC guidelines : improving the quality [PDF]

CDC GUIDELINES: Improving the Quality is a guide to improve the development processes, content, and value of CDC-sponsored practice guidelines. The guide presents \u201cpoints to consider\u201d and \u201crecommendations\u201d which should be given ...

core  

Paying clinicians to join clinical trials : a review of guidelines and interview study of trialists [PDF]

, 2009
Background: The motivations of clinicians to participate in clinical trials have been little studied. This project explored the potential role of payment for participation in publicly funded clinical trials in the UK.
Raftery James, Kerr Christine, Hawker, Sheila, Powell John, Powell, John, Hawker Sheila, Raftery, James, Kerr, Christine   +7 more
core   +1 more source

Challenges and considerations in the management of acute pulmonary embolism: A critical analysis of European Society of Cardiology guidelines [PDF]

Vojnosanitetski Pregled
nema
Obradović Slobodan, Džudović Boris, Simpson Tamara   +2 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Designing tailored maintenance strategies for systematic reviews and clinical practice guidelines using the Portfolio Maintenance by Test-Treatment (POMBYTT) framework

BMC Medical Research Methodology
Background Organizations face diverse contexts and requirements when updating and maintaining their portfolio, or pool, of systematic reviews or clinical practice guidelines they need to manage.
Michiel S. Oerbekke, Roy G. Elbers, Maarten J. van der Laan, Lotty Hooft   +3 more
doaj   +1 more source

Impact of using a local protocol in preoperative testing: blind randomized clinical trial.

Revista do Colégio Brasileiro de Cirurgiões
Objective: to evaluate the impact of the use of a local protocol of preoperative test requests in reducing the number of exams requested and in the occurrence of changes in surgical anesthetic management and perioperative complications.
MÔNICA LOUREIRO SANTOS, ANTÔNIO CARLOS IGLESIAS   +1 more
doaj   +1 more source