Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs
Here, we have established an antigen-specific single B cell sorting and monoclonal antibody (mAb) cloning platform for analyzing immunization- or viral infection-elicited antibody response at the clonal level in guinea pigs.
Lin Lei+9 more
doaj +3 more sources
Establishment and optimization of an in vitro guinea pig oocyte maturation system.
Guinea pigs are a valuable animal model for studying various diseases, including reproductive diseases. However, techniques for generating embryos via embryo engineering in guinea pigs are limited; for instance, in vitro maturation (IVM) technique is ...
Minhua Yao+10 more
doaj +1 more source
Morphological and morphometric characterization of the guinea pig sperm (Cavia porcellus) [PDF]
The aim of this study was to determine the morphological and morphometric characteristics of guinea pig sperm (Cavia porcellus), using an image analysis system.
Urbano Cabeza+3 more
doaj +1 more source
Severe allergic reactions to guinea pig
Background Allergic sensitization and reactions to guinea pig (Cavia porcellus) have been well documented in laboratory animal handlers, primarily manifesting as rhinitis, conjunctivitis, and asthma. Severe allergic reactions, however, are rare.
Shaw Jeffrey L+3 more
doaj +1 more source
Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands. [PDF]
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that mediates many of the biological and toxicological actions of structurally diverse chemicals.
Bonati, Laura+10 more
core +3 more sources
Not more than three tissue kallikreins identified from organs of the guinea pig [PDF]
The large and varied multigene families of tissue kallikreins of rat and mouse are considered to selectively release as many bioactive peptides. In order to determine whether a similar family of enzymes is expressed in the organs of the guinea pig ...
Geiger+6 more
core +1 more source
Not so presto? Outcomes of sluggish prestin in outer hair cells [PDF]
Prestin (SLC26A5), a protein essential for the sensitivity of the mammalian ear, was so named from \emph{presto}. The assumption was that this membrane protein supports fast movement of outer hair cells (OHCs) that matches the mammalian hearing range, up to 20 kHz in general and beyond, depending on the species.
arxiv +1 more source
Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. [PDF]
Eosinophil accumulation is a prominent feature of allergic inflammatory reactions, such as those occurring in the lung of the allergic asthmatic, but the endogenous chemoattractants involved have not been identified.
Collins, PD+8 more
core +1 more source
Domestic guinea pig is a model animal for human disease research. Uridine diphosphate glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) is an important human disease-related gene. In this study, the complete coding sequence of domestic guinea pig
Yang Deming, An Qingcong, Liu Yonggang
doaj +1 more source
Guinea Pig and Rat as Carriers of Host-unique and Shared Haemophilus Phenotypes [PDF]
Infections by V- factor dependent Pasteurellaceae (commonly called Haemophilus spp) frequently occur in colonies of guinea pig and rat. We evaluated possible differences between 185 Haemophilus strains from guinea pig (n=97) and rat (n=88) by API NH ...
Boot, R
core +2 more sources