Development and validation of a Guinea pig model for concurrent allergic rhinitis and asthma using recombinant Der f 2. [PDF]
Xu F, Hu L, Wang J, Zhang L.
europepmc +1 more source
Modeling cerebral palsy in animals
Abstract Advancements in the treatment of cerebral palsy depend on animal research. Yet, most animal models have not been fully evaluated for spasticity and dystonia using clinically relevant measures of altered tone or movement patterns, which form the basis for diagnosing people with the condition.
Katharina A. Quinlan +8 more
wiley +1 more source
Formulation and Evaluation of Valproic Acid Microemulsions for Enhanced Transfollicular Delivery in Guinea Pig Skin. [PDF]
Salimi A +3 more
europepmc +1 more source
Loss of E3 ligase HvST1 function substantially increases distal crossover frequency
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr +8 more
wiley +1 more source
Electroanatomical adaptations in the guinea pig heart from neonatal to adulthood. [PDF]
Haq KT +4 more
europepmc +1 more source
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen +13 more
wiley +1 more source
Development and characterization of a reverse genetics system for the lineage II Chicava strain of Machupo virus in a guinea pig model. [PDF]
Mantlo E +5 more
europepmc +1 more source
Extracellular Matrix Viscoelasticity Regulates Mammary Branching Morphogenesis
This study shows that mammary branching morphogenesis is regulated by extracellular matrix (ECM) stress relaxation. Slow stress‐relaxing matrices promote branching through focal adhesion signaling, collagen fiber alignment, and cell contractions, whereas fast stress‐relaxing matrices impair branching and collagen alignment.
Daniella I. Walter +3 more
wiley +1 more source
CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infections. [PDF]
Rollman TB +9 more
europepmc +1 more source
The fine structure and organization of tip links on hair cell stereovilli [PDF]
Brix, Jutta +6 more
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