Results 281 to 290 of about 911,964 (393)

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

Expression of Concern: Adipose-derived stromal cell therapy affects lung inflammation and tracheal responsiveness in Guinea Pig model of COPD. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

Comparative Assessment of Functional and Morphological Markers in Guinea Pig (<i>Cavia porcellus</i>) Oocytes Collected at Different Estrous Cycle Phases. [PDF]

Animals (Basel)
Samaniego JX, Pesántez JL, Perea FP, Pazmiño AP, Dután JB, Ruiz S.   +5 more
europepmc   +1 more source

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev, Alexey V. Glukhov, Vladimir Bogdanov, Aleksei S. Averin, Roland Veress, Bum‐Rak Choi, Shanna Hamilton, Andriy E. Belevych   +7 more
wiley   +1 more source

Replication-deficient whole-virus vaccines against cytomegalovirus induce protective immunity in a guinea pig congenital infection model. [PDF]

J Virol
Schleiss MR, Fernández-Alarcón C, Bierle CJ, Geballe AP, Badillo-Guzman A, Tanna CE, Tsriwong K, Blackstad M, Wang JB, McVoy MA.   +9 more
europepmc   +1 more source

Correction: Mangiferin Prevents Guinea Pig Tracheal Contraction via Activation of the Nitric Oxide-Cyclic GMP Pathway

, 2013

openalex   +1 more source

Preclinical Evaluation of the Safety of the Dedicated Gel for Gel Immersion Endoscopy With Gastrointestinal Perforation and Peritoneal Leakage

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Gel immersion endoscopic mucosal resection or endoscopic submucosal dissection has been developed as an alternative to saline immersion therapeutic endoscopy. However, in cases of gastrointestinal perforation, gel may leak from the lumen into the peritoneal cavity, and the safety of such events remains unclarified.
Atsushi Ohata, Ryo Kawahara, Yuji Hiraki, Hikaru Nakata, Shinya Kaneda, Tomonori Yano   +5 more
wiley   +1 more source

Aurantio-Obtusin Suppresses Airway Inflammation and Serum ICAM-1 Expression in Guinea Pig Allergic Asthma Model. [PDF]

Immun Inflamm Dis
Nyarko MS, Danquah CA, Antwi AO, Emikpe BO, Osafo N.   +4 more
europepmc   +1 more source

Maternal Milk Allopregnanolone May Buffer Negative Associations Between Maternal Postpartum Psychological Distress and Infant Regulatory Capacity

Developmental Psychobiology, Volume 68, Issue 2, March 2026.
ABSTRACT Maternal psychological distress during pregnancy and the early postpartum period is a risk factor for dysregulated affective and regulatory function in young infants. Animal models suggest that perinatal stress may alter offspring development via allopregnanolone (ALLO) exposure.
Denise M. Werchan, Bradley Susskind, Rebecca Carpio, Brittany R. Howell, Natalie H. Brito, Moriah E. Thomason   +5 more
wiley   +1 more source