Results 61 to 70 of about 386,087 (352)

Development and Evaluation of a Direct Sandwich Enzyme-Linked Immunosorbent Assay for the Quantification of Guinea-Pig Immunoglobulin E

Journal of Pharmacological Sciences, 2006
.: The purpose of this study was to develop and evaluate a direct sandwich enzyme-linked immunosorbent assay (ELISA) for the immunoglobulin E (IgE) in serum and plasma from guinea pig using mouse monoclonal antibodies specific for guinea-pig IgE.
Nishimura Makoto, Funaoka Hiroyuki, Hosoe Hiroaki, Ohkaru Yasuhiko, Yakuo Ikuhisa, Hayakawa Shinobu, Ito Koji   +6 more
doaj   +1 more source

Conductance Changes of Na⁺ Channels during the Late Na⁺ Current Flowing under Action Potential Voltage Clamp Conditions in Canine, Rabbit, and Guinea Pig Ventricular Myocytes

Pharmaceuticals, 2023
Late sodium current (INa,late) is an important inward current contributing to the plateau phase of the action potential (AP) in the mammalian heart. Although INa,late is considered as a possible target for antiarrhythmic agents, several aspects of this ...
Balázs Horváth, Zsigmond M. Kovács, Csaba Dienes, József Óvári, Norbert Szentandrássy, János Magyar, Tamás Bányász, András Varró, Péter P. Nánási   +8 more
doaj   +1 more source

Identity and Function of a Cardiac Mitochondrial Small Conductance Ca2+-Activated K+ Channel Splice Variant [PDF]

, 2017
We provide evidence for location and function of a small conductance, Ca2+-activated K+ (SKCa) channel isoform 3 (SK3) in mitochondria (m) of guinea pig, rat and human ventricular myocytes. SKCa agonists protected isolated hearts and mitochondria against
Aldakkak, Mohammed, Camara, Amadou K. S., Kwok, Wai-Meng, Stowe, David F., Yang, MeiYing   +4 more
core   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Pacing Dynamics Determines the Arrhythmogenic Mechanism of the CPVT2-Causing CASQ2G112+5X Mutation in a Guinea Pig Ventricular Myocyte Computational Model [PDF]

, 2022
Roshan Paudel, M. Saleet Jafri, Aman Ullah   +2 more
openalex   +1 more source

Perubahan Tinggi Sel Epitelium Villi Ventrikulus Marmut (Cavia porcellus L.) Setelah Pemberian Teh Hijau [PDF]

, 2014
The research of the of Guniea Pig Ventriculus Villi Epithelium Cell Height After Was Given With Green Tea is aimed to know the effect of green tea on ventriculus villi epithelium cell height of female guinea pig.
Kasiyati, Kasiyati, Muliani, Hirawati
core   +1 more source

Identification of the prostanoid receptor mediating PGE2-induced cough

, 2009
Prostaglandin E2 (PGE2) may provide a novel therapy for the treatment of inflammatory airway diseases as it has been shown to confer both bronchodilator and anti-inflammatory activity in asthmatic subjects.
Maher, Ann, Maher, Ann
core   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

GUINEA-PIG++ : an upgraded version of the linear collider beam-beam interaction simulation code GUINEA-PIG [PDF]

, 2007
http://cern.ch/AccelConf/p07/PAPERS/THPMN010.PDFInternational audienceGUINEA-PIG++ is a newly developed object-oriented version of the Linear Collider beam-beam simulation program GUINEA-PIG.
Bambade, P., Dadoun, O., del C. Alabau Pons, M., Le Meur, G., Rimbault, Cécile, Schulte, D., Touze, F.   +6 more
core   +2 more sources

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source