Results 61 to 70 of about 235,648 (296)

Penggunaan Mencit untuk Pemeriksaan Potensi Toksoid Difteri [PDF]

open access: yes, 1987
At present, the potency test of diphtheria toxoid is carried out on Guinea pigs as experimental animals. Production of a large number of Guinea pigs suitable for experiment is still, considered to be a substantial problem, especially in some developing ...
Isbagio, D. W. (Dyah)   +3 more
core  

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

open access: yesAdvanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo   +16 more
wiley   +1 more source

Pharmacokinetics and absolute oral bioavailability of meloxicam in guinea pigs (Cavia porcellus)

open access: yes, 2019
Objective: To investigate the pharmacokinetics and absolute oral bioavailability of meloxicam in guinea pigs. Study design: Prospective crossover study. Animals: A group of six healthy male Dunkin Hartley guinea pigs.
Croubels, Siska   +4 more
core   +1 more source

The role of external broadcasting in a closed political system [PDF]

open access: yes, 2011
This article investigates the role and impact of external broadcasting (radio and television) on a closed political system, through the example of the two post-war German states: the West German Federal Republic of Germany (FRG) and the East German ...
Andreas Scheu   +23 more
core   +2 more sources

Determinants of Childhood Zoonotic Enteric Infections in a Semirural Community of Quito, Ecuador. [PDF]

open access: yes, 2020
Domestic animals in the household environment have the potential to affect a child's carriage of zoonotic enteric pathogens and risk of diarrhea. This study examines the risk factors associated with pediatric diarrhea and carriage of zoonotic enteric ...
Eisenberg, Joseph NS   +9 more
core   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

open access: yesAdvanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu   +11 more
wiley   +1 more source

Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature [PDF]

open access: yes, 2017
Rabbits and guinea pigs are increasingly popular pets in the UK, yet little is known about their common ailments, or how these relate to what appears in the published literature.
Brennan, Marnie L.   +3 more
core   +2 more sources

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

open access: yesAdvanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang   +16 more
wiley   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

. Preliminary data on nematode infections in guinea pigs in the province of Cajabamba (Cajamarca, Peru)

open access: yesBulgarian Journal of Veterinary Medicine
In the absence of local studies, the current study was conducted in four villages located in the province of Cajabamba (Cajamarca, Peru) to demonstrate and determine the point prevalence of enteric nematodes in guinea pigs (Cavia porcellus) raised in a ...
K. Tacilla   +4 more
doaj   +1 more source

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