Results 161 to 170 of about 68,405 (219)

Farnesol, the farnesol pathway, and the immune-gut-brain axis. [PDF]

Front Pharmacol
Gates M, Schumacher SM, Doyle WJ, Sofaly N, Roullet JB, Ochoa-Repáraz J.   +5 more
europepmc   +1 more source

Pioneering the canine model in microbiota–gut–brain research for social and affective disorders

iMetaOmics, EarlyView.
This commentary highlights the translational potential of canine models in investigating the microbiota–gut–brain (MGB) axis, focusing on their relevance to human social cognition and affective disorders, including major depressive disorder and autism spectrum disorder.
Yun Yu, Qiuhan Wen, Xiaoyang Wang, Mengyu Song, Tifei Yuan, Feilong Deng, Jianmin Chai, Ying Li, Ya‐Ping Zhang   +8 more
wiley   +1 more source

The role of the gut mycobiota in neurodevelopmental disorders: a multikingdom disruption of the gut-brain axis. [PDF]

Front Microbiol
Hu Y, Yu XL, Zhang XJ, Ma LT.
europepmc   +1 more source

Integrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis

iMeta, EarlyView.
Liver cirrhosis is associated with profound disruption of host–microbiome metabolic interactions. Using paired oral and fecal metagenomics combined with genome‐scale metabolic modeling, we investigated how microbial translocation along the oral–gut axis influences microbial metabolism at different cirrhosis severities.
Yi Jin, Frederick Clasen, Fernando Garcia‐Guevara, Sania Arif, Robert Schierwagen, Gholamreza Bidkhori, Michael Praktiknjo, Maximilian J. Brol, Frank E. Uschner, Florence A. Castelli, Nicolas Pons, Benoit Quinquis, Nathalie Galleron, Kevin Da Silva, Christophe Junot, Debbie L. Shawcross, David L. Moyes, Rajiv Jalan, S. Dusko Ehrlich, Vishal C. Patel, Jonel Trebicka, Saeed Shoaie   +21 more
wiley   +1 more source

The gut-brain axis in avian appetite regulation: Integrating peripheral signals with central neurocircuitry. [PDF]

Poult Sci
Mahdavi K, Zendehdel M, Ghashghaei E, Lin H.   +3 more
europepmc   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Intestinal macrophages modulate synucleinopathy along the gut-brain axis. [PDF]

Nature
De Schepper S, Konstantellos V, Conway JA, Sokolova D, Zaccagnini L, Cowley MV, Sierksma A, Yudina M, Edmonds M, Gavriouchkina D, Geary B, Wallis A, Celikag M, Baykam Z, Vara-Pérez M, Crowley G, Hager FT, Bijnen M, Posner D, Luk K, Cerovic V, Clatworthy M, Videlock EJ, Jaunmuktane Z, Movahedi K, Greter M, Chain B, Alessi DR, Hong S, Bartels T.   +29 more
europepmc   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Pharmacological interventions targeting the gut-brain axis in neurological disorders: mechanisms and translational applications. [PDF]

Front Neurosci
Li X, Zhou W, Yang S, Huang X, Zheng K.
europepmc   +1 more source