Results 61 to 70 of about 155,705 (354)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Remyelination and the gut−brain axis [PDF]
Proceedings of the National Academy of Sciences, 2019 Multiple sclerosis (MS) is a neuroinflammatory disease of the central nervous system (CNS) that affects over 2.5 million people worldwide. Most patients develop a relapsing−remitting disease in their second or third decade, although some have a progressive disease from onset.
Ian D, Duncan, Jyoti J, Watters
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Microbiota-gut-brain axis and nutritional strategy under heat stress
Animal Nutrition, 2021 Heat stress is a very universal stress event in recent years. Various lines of evidence in the past literatures indicate that gut microbiota composition is susceptible to variable temperature.
Chaoyue Wen +4 more
doaj +1 more source
An overview of the effect of probiotics and exercise on mood and associated health conditions [PDF]
, 2016 The present paper provides a review of the current knowledge relating to the health benefits of probiotics, specially focused on the effects they may have together with physical exercise on mood disorders and related chronic medical conditions. With both
Baker, Julien S., Grant, Marie Clare
core +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Sex-dependent effects of a high-fat diet on the hypothalamic response in mice
Biology of Sex DifferencesSex differences in rodent models of diet-induced obesity are still poorly documented, particularly regarding how central mechanisms vary between sexes in response to an obesogenic diet.
Virginie Dreux +9 more
doaj +1 more source
Gut MicrobesThe role of the microbiota‒gut‒brain axis in the pathophysiology of anorexia nervosa has emerged in recent decades. Increased expression of Toll-like receptor 4 (TLR4) has been reported in the intestinal epithelial cells (IEC) of activity-based anorexia (
Colin Salaün +12 more
doaj +1 more source
The gut-brain axis in ischemic stroke: its relevance in pathology and as a therapeutic target
Neurological Research and Practice, 2022 The gut contains the largest reservoir of microorganisms of the human body, termed as the gut microbiota which emerges as a key pathophysiological factor in health and disease. The gut microbiota has been demonstrated to influence various brain functions
Corinne Benakis, Arthur Liesz
doaj +1 more source
Dysregulated Glycerophospholipid Metabolism and ChAT Overexpression in Wrap-Restraint Stress-Induced IBS Mice: A Multi-Omics Approach to Gut-Brain Axis Disruption and Potential Therapeutic Targets [PDF]
, 2023 Fan Zhang +6 more
openalex +1 more source