Results 51 to 60 of about 154,180 (306)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hunger and Satiety Mechanisms and Their Potential Exploitation in the Regulation of Food Intake [PDF]
, 2016 Acknowledgments Tehmina Amin is the Project Manager and Julian Mercer is Project Coordinator for Full4Health. Both are funded by the Full4Health project (grant agreement no. 266408) under the EU Seventh Framework Programme (FP7/2007–2013).
Amin, Tehmina, Mercer, Julian G.
core +2 more sources
Remyelination and the gut−brain axis [PDF]
Proceedings of the National Academy of Sciences, 2019 Multiple sclerosis (MS) is a neuroinflammatory disease of the central nervous system (CNS) that affects over 2.5 million people worldwide. Most patients develop a relapsing−remitting disease in their second or third decade, although some have a progressive disease from onset.
Ian D, Duncan, Jyoti J, Watters
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A pilot study on the effects of probiotic supplementation on neuropsychological performance and microRNA-29a-c levels in antiretroviral-treated HIV-1-infected patients [PDF]
, 2017 The gut microbiota is involved in the regulation of cognition, mood, anxiety, and pain, and can impact cognitive functions by producing neuroactive substances or releasing bacterial by-products and metabolites.
Anukam +41 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Sex-dependent effects of a high-fat diet on the hypothalamic response in mice
Biology of Sex DifferencesSex differences in rodent models of diet-induced obesity are still poorly documented, particularly regarding how central mechanisms vary between sexes in response to an obesogenic diet.
Virginie Dreux +9 more
doaj +1 more source
BMJ OpenBackground Alzheimer’s disease (AD) impacts over 55 million individuals worldwide and remains the leading cause of dementia (60–70% of cases). By 2050, South and Southeast Asia are projected to have an older adult population more than double, bearing a ...
Zhahirul Islam +9 more
doaj +1 more source
Microbiota-gut-brain axis and nutritional strategy under heat stress
Animal Nutrition, 2021 Heat stress is a very universal stress event in recent years. Various lines of evidence in the past literatures indicate that gut microbiota composition is susceptible to variable temperature.
Chaoyue Wen +4 more
doaj +1 more source
Intestinal microbiota influences non-intestinal related autoimmune diseases [PDF]
, 2018 Indexación: Scopus.The human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner.
Bonifaz, L.C. +8 more
core +2 more sources