Results 31 to 40 of about 154,180 (306)

Gut microbiota, metabolism and psychopathology:A critical review and novel perspectives [PDF]

, 2018
Psychiatric disorders are often associated with metabolic comorbidities. However, the mechanisms through which metabolic and psychiatric disorders are connected remain unclear.
de Clercq, Nicolien C, Groen, Albert K, Groen, Robin N, Hoenders, H J Rogier, Nieuwdorp, Max   +4 more
core   +2 more sources

Gut/brain axis and the microbiota [PDF]

Journal of Clinical Investigation, 2015
Tremendous progress has been made in characterizing the bidirectional interactions between the central nervous system, the enteric nervous system, and the gastrointestinal tract. A series of provocative preclinical studies have suggested a prominent role for the gut microbiota in these gut-brain interactions.
Mayer, Emeran A, Tillisch, Kirsten, Gupta, Arpana   +2 more
openaire   +4 more sources

Pain determinants and quality of life in Guillain-Barre syndrome: a prospective cohort study

BMJ Neurology Open
Background Pain is a serious manifestation in both the acute and chronic stages of Guillain-Barre syndrome (GBS). We evaluated the frequency, characteristics and associated factors of pain and its impact on quality of life (QoL) among patients with GBS ...
Badrul Islam, Zhahirul Islam, Israt Jahan, Gulshan Ara, Nowshin Papri, Asif Mohammed, Md. Mantaka Rahman, Imran Hasan, Rufydha Azam, Tamal Saha, Farzana Tamanna Ummey Shaon, Shoma Hayat   +11 more
doaj   +1 more source

SLAB51 Probiotic Formulation Activates SIRT1 Pathway Promoting Antioxidant and Neuroprotective Effects in an AD Mouse Model [PDF]

, 2018
The gut-brain axis is a bidirectional communication network functionally linking the gut and the central nervous system (CNS). Based on this, the rational manipulation of intestinal microbiota represents a novel attractive therapeutic strategy for the ...
Angeletti, Mauro, Berardi, Sara, Bonfili, Laura, Cecarini, Valentina, Cuccioloni, Massimiliano, Eleuteri, Anna Maria, Rossi, Giacomo, Scarpona, Silvia   +7 more
core   +1 more source

Obesity and Appetite Control [PDF]

, 2012
Obesity is one of the major challenges to human health worldwide; however, there are currently no effective pharmacological interventions for obesity.
Bloom, SR, Jayasena, CN, Suzuki, K
core   +2 more sources

Genomic variability of lipooligosaccharide biosynthesis locus and sequence type among Campylobacter jejuni isolated from patients with Guillain-Barré syndrome

Microbiology Spectrum
Lipooligosaccharide (LOS) is a crucial component of the Campylobacter jejuni (C. jejuni) cell membrane that mimics human gangliosides and can induce autoimmune neuropathies like Guillain-Barré syndrome (GBS). Approximately one in 1,000 C.
Md. Abu Jaher Nayeem, Shoma Hayat, Asaduzzaman Asad, Md. Golam Mostafa, Shah Nayeem Faruque, Ruma Begum, Mosabbir Ahmed, Yearul Kabir, Israt Jahan, Zhahirul Islam   +9 more
doaj   +1 more source

PD-1/PD-L1 Axis Downregulation in Guillain-Barré Syndrome: A Potential Mechanism Driving the Autoimmune Pathogenesis

International Journal of Infectious Diseases
Introduction: Guillain-Barré syndrome (GBS), an immune-mediated disorder of the peripheral nervous system characterized by progressive muscle weakness, is often triggered by Campylobacter jejuni infection. Molecular mimicry between C.
Mr Rasel Ahmed, Mrs Israt Jahan, Mrs Pritha Biswash, Miss Mehjabeen Haque, Miss Sarah Khurshid, Mr Jigishu Ahmed, Mr Sayed Akib Hossain, Dr Zhahirul Islam   +7 more
doaj   +1 more source

Resistome phylodynamics of multidrug-resistant Shigella isolated from diarrheal patients

Microbiology Spectrum
Multi-drug resistance (MDR) in Shigella continues to pose a significant public health challenge, particularly in developing countries. Recent advances in genomics strengthen the surveillance of MDR-pathogens and antimicrobial resistance (AMR) mediators ...
Asaduzzaman Asad, Md. Abu Jaher Nayeem, Md. Golam Mostafa, Ruma Begum, Shah Nayeem Faruque, Suraia Nusrin, Israt Jahan, Shoma Hayat, Zhahirul Islam   +8 more
doaj   +1 more source

Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling

Nature Communications, 2019
Early life stress has been associated with the occurrence of gastrointestinal diseases later in life, but underlying mechanisms remain poorly understood. Here, Wong et al.
Hoi Leong Xavier Wong, Hong-yan Qin, Siu Wai Tsang, Xiao Zuo, Sijia Che, Chi Fung Willis Chow, Xi Li, Hai-tao Xiao, Ling Zhao, Tao Huang, Cheng Yuan Lin, Hiu Yee Kwan, Tao Yang, Frank M. Longo, Aiping Lyu, Zhao-xiang Bian   +15 more
doaj   +1 more source

Towards large-cohort comparative studies to define the factors influencing the gut microbial community structure of ASD patients. [PDF]

, 2015
Differences in the gut microbiota have been reported between individuals with autism spectrum disorders (ASD) and neurotypical controls, although direct evidence that changes in the microbiome contribute to causing ASD has been scarce to date.
Debelius, Justine, Gilbert, Jack A, Hornig, Mady, Knight, Rob, Lozupone, Catherine, McDonald, Daniel   +5 more
core   +3 more sources