Results 11 to 20 of about 68,405 (219)

Gut–brain axis: Synergistic approach

Industrial Psychiatry Journal, 2021
Since decades, there is a change in concept of the gut–brain axis. There is differential increase in evidences focusing on the bidirectional communication between the gut microbiome and the brain. It supports existence of far-reaching model of “gut–brain
Markanday Sharma, Jyoti Prakash, Prateek Yadav, Kalpana Srivastava, Kaushik Chatterjee   +4 more
doaj   +1 more source

Pain determinants and quality of life in Guillain-Barre syndrome: a prospective cohort study

BMJ Neurology Open
Background Pain is a serious manifestation in both the acute and chronic stages of Guillain-Barre syndrome (GBS). We evaluated the frequency, characteristics and associated factors of pain and its impact on quality of life (QoL) among patients with GBS ...
Badrul Islam, Zhahirul Islam, Israt Jahan, Gulshan Ara, Nowshin Papri, Asif Mohammed, Md. Mantaka Rahman, Imran Hasan, Rufydha Azam, Tamal Saha, Farzana Tamanna Ummey Shaon, Shoma Hayat   +11 more
doaj   +1 more source

Crosstalk between the aging intestinal microflora and the brain in ischemic stroke

Frontiers in Aging Neuroscience, 2022
Aging is an inevitable phenomenon experienced by animals and humans, and its intensity varies from one individual to another. Aging has been identified as a risk factor for neurodegenerative disorders by influencing the composition of the gut microbiota,
Ryszard Pluta, Mirosław Jabłoński, Sławomir Januszewski, Stanisław J. Czuczwar   +3 more
doaj   +1 more source

Genomic variability of lipooligosaccharide biosynthesis locus and sequence type among Campylobacter jejuni isolated from patients with Guillain-Barré syndrome

Microbiology Spectrum
Lipooligosaccharide (LOS) is a crucial component of the Campylobacter jejuni (C. jejuni) cell membrane that mimics human gangliosides and can induce autoimmune neuropathies like Guillain-Barré syndrome (GBS). Approximately one in 1,000 C.
Md. Abu Jaher Nayeem, Shoma Hayat, Asaduzzaman Asad, Md. Golam Mostafa, Shah Nayeem Faruque, Ruma Begum, Mosabbir Ahmed, Yearul Kabir, Israt Jahan, Zhahirul Islam   +9 more
doaj   +1 more source

PD-1/PD-L1 Axis Downregulation in Guillain-Barré Syndrome: A Potential Mechanism Driving the Autoimmune Pathogenesis

International Journal of Infectious Diseases
Introduction: Guillain-Barré syndrome (GBS), an immune-mediated disorder of the peripheral nervous system characterized by progressive muscle weakness, is often triggered by Campylobacter jejuni infection. Molecular mimicry between C.
Mr Rasel Ahmed, Mrs Israt Jahan, Mrs Pritha Biswash, Miss Mehjabeen Haque, Miss Sarah Khurshid, Mr Jigishu Ahmed, Mr Sayed Akib Hossain, Dr Zhahirul Islam   +7 more
doaj   +1 more source

Resistome phylodynamics of multidrug-resistant Shigella isolated from diarrheal patients

Microbiology Spectrum
Multi-drug resistance (MDR) in Shigella continues to pose a significant public health challenge, particularly in developing countries. Recent advances in genomics strengthen the surveillance of MDR-pathogens and antimicrobial resistance (AMR) mediators ...
Asaduzzaman Asad, Md. Abu Jaher Nayeem, Md. Golam Mostafa, Ruma Begum, Shah Nayeem Faruque, Suraia Nusrin, Israt Jahan, Shoma Hayat, Zhahirul Islam   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multidrug-resistant conjugative plasmid carrying mphA confers increased antimicrobial resistance in Shigella

Scientific Reports
Shigellosis remains a common gastrointestinal disease mostly in children 
Asaduzzaman Asad, Israt Jahan, Moriam Akter Munni, Ruma Begum, Morium Akter Mukta, Kazi Saif, Shah Nayeem Faruque, Shoma Hayat, Zhahirul Islam   +8 more
doaj   +1 more source

Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling

Nature Communications, 2019
Early life stress has been associated with the occurrence of gastrointestinal diseases later in life, but underlying mechanisms remain poorly understood. Here, Wong et al.
Hoi Leong Xavier Wong, Hong-yan Qin, Siu Wai Tsang, Xiao Zuo, Sijia Che, Chi Fung Willis Chow, Xi Li, Hai-tao Xiao, Ling Zhao, Tao Huang, Cheng Yuan Lin, Hiu Yee Kwan, Tao Yang, Frank M. Longo, Aiping Lyu, Zhao-xiang Bian   +15 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source