Results 111 to 120 of about 2,005,973 (405)
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld+7 more
wiley +1 more source
Apprendre. Oui, mais comment ?
Apprendre. Oui, mais comment ? Cette question posée par Philippe Meirieu (1991) au début des années quatre-vingt reste toujours d’actualité. Dans la présente communication je m’attache à examiner la notion d’apprendre.
Dagmara Gut
doaj +1 more source
A 71‐year‐old obese woman was referred to our hospital with lower left abdominal pain. Computed tomography showed a 46 mm elliptic calcification lodged in the sigmoid‐descending colon junction (SDJ), which had been detected 5 years prior but was not ...
Tadataka Takagi+9 more
doaj +1 more source
OBJECTIVE—Diabetes and obesity are characterized by a low-grade inflammation whose molecular origin is unknown. We previously determined, first, that metabolic endotoxemia controls the inflammatory tone, body weight gain, and diabetes, and second, that ...
Patrice D Cani+6 more
semanticscholar +1 more source
Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis
Gut microbiota encompasses a wide variety of commensal microorganisms consisting of trillions of bacteria, fungi, and viruses. This microbial population coexists in symbiosis with the host, and related metabolites have profound effects on human health ...
P. Portincasa+9 more
semanticscholar +1 more source
Immunoglobulin A and liver diseases. [PDF]
Immunoglobulin A (IgA) is a major immunoglobulin isotype in the gut and plays a role in maintenance of gut homeostasis. Secretory IgA (SIgA) has multiple functions in the gut, such as to regulate microbiota composition, to protect intestinal epithelium ...
Inamine, Tatsuo, Schnabl, Bernd
core
Factors Associated with the Diversification of the Gut Microbial Communities within Chimpanzees from Gombe National Park. [PDF]
The gastrointestinal tract harbors large and diverse populations of bacteria that vary among individuals and within individuals over time. Numerous internal and external factors can influence the contents of these microbial communities, including diet ...
A. E. Pusey+26 more
core +1 more source
Mass-Splitting between Haves and Have-Nots (Symmetry vs. Grand Unified Theory) [PDF]
We revisit the long-standing problem of supersymmetric grand unified theory (GUT), the doublet-triplet splitting problem. We discuss whether symmetry which controls the {\mu} term in the minimal supersymmetric standard model is compatible with GUT. We find that the symmetry must be broken at the GUT scale.
arxiv +1 more source
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang+8 more
wiley +1 more source
Short-chain fatty acids (SCFAs), the end products of fermentation of dietary fibers by the anaerobic intestinal microbiota, have been shown to exert multiple beneficial effects on mammalian energy metabolism.
G. den Besten+5 more
semanticscholar +1 more source