Results 111 to 120 of about 2,005,973 (405)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Apprendre. Oui, mais comment ?

open access: yesMosaïque, 2011
Apprendre. Oui, mais comment ? Cette question posée par Philippe Meirieu (1991) au début des années quatre-vingt reste toujours d’actualité. Dans la présente communication je m’attache à examiner la notion d’apprendre.
Dagmara Gut
doaj   +1 more source

Colonic gallstone ileus treated by a transanal ileus tube followed by spontaneous gallstone dislodgement: A case report

open access: yesDEN Open, 2023
A 71‐year‐old obese woman was referred to our hospital with lower left abdominal pain. Computed tomography showed a 46 mm elliptic calcification lodged in the sigmoid‐descending colon junction (SDJ), which had been detected 5 years prior but was not ...
Tadataka Takagi   +9 more
doaj   +1 more source

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice

open access: yesDiabetes, 2008
OBJECTIVE—Diabetes and obesity are characterized by a low-grade inflammation whose molecular origin is unknown. We previously determined, first, that metabolic endotoxemia controls the inflammatory tone, body weight gain, and diabetes, and second, that ...
Patrice D Cani   +6 more
semanticscholar   +1 more source

Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis

open access: yesInternational Journal of Molecular Sciences, 2022
Gut microbiota encompasses a wide variety of commensal microorganisms consisting of trillions of bacteria, fungi, and viruses. This microbial population coexists in symbiosis with the host, and related metabolites have profound effects on human health ...
P. Portincasa   +9 more
semanticscholar   +1 more source

Immunoglobulin A and liver diseases. [PDF]

open access: yes, 2018
Immunoglobulin A (IgA) is a major immunoglobulin isotype in the gut and plays a role in maintenance of gut homeostasis. Secretory IgA (SIgA) has multiple functions in the gut, such as to regulate microbiota composition, to protect intestinal epithelium ...
Inamine, Tatsuo, Schnabl, Bernd
core  

Factors Associated with the Diversification of the Gut Microbial Communities within Chimpanzees from Gombe National Park. [PDF]

open access: yes, 2012
The gastrointestinal tract harbors large and diverse populations of bacteria that vary among individuals and within individuals over time. Numerous internal and external factors can influence the contents of these microbial communities, including diet ...
A. E. Pusey   +26 more
core   +1 more source

Mass-Splitting between Haves and Have-Nots (Symmetry vs. Grand Unified Theory) [PDF]

open access: yes, 2015
We revisit the long-standing problem of supersymmetric grand unified theory (GUT), the doublet-triplet splitting problem. We discuss whether symmetry which controls the {\mu} term in the minimal supersymmetric standard model is compatible with GUT. We find that the symmetry must be broken at the GUT scale.
arxiv   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

open access: yesJournal of Lipid Research, 2013
Short-chain fatty acids (SCFAs), the end products of fermentation of dietary fibers by the anaerobic intestinal microbiota, have been shown to exert multiple beneficial effects on mammalian energy metabolism.
G. den Besten   +5 more
semanticscholar   +1 more source

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