Results 131 to 140 of about 56,089 (298)

Flora: Efficient Cloud Resource Selection for Big Data Processing via Job Classification [PDF]

open access: yesarXiv
Distributed dataflow systems like Spark and Flink enable data-parallel processing of large datasets on clusters of cloud resources. Yet, selecting appropriate computational resources for dataflow jobs is often challenging. For efficient execution, individual resource allocations, such as memory and CPU cores, must meet the specific resource demands of ...
arxiv  

Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong   +7 more
wiley   +1 more source

Chemical Process Development in the Pharmaceutical Industry in Europe—Insights and Perspectives from Industry Scientists

open access: yesAngewandte Chemie, EarlyView.
What are the tasks of chemical process development in the pharmaceutical industry? What are trends and challenges? This Scientific Perspective written by members of the European pharmaceutical industry introduces key concepts of drug development and key drivers for the future of chemical process development.
Joachim Krueger   +12 more
wiley   +2 more sources

Synbiotic modulation of gut flora: Effect on minimal hepatic encephalopathy in patients with cirrhosis [PDF]

open access: bronze, 2004
Qing Liu   +5 more
openalex   +1 more source

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang   +6 more
wiley   +1 more source

Dressing the Imagination: A Dataset for AI-Powered Translation of Text into Fashion Outfits and A Novel KAN Adapter for Enhanced Feature Adaptation [PDF]

open access: yesarXiv
Specialized datasets that capture the fashion industry's rich language and styling elements can boost progress in AI-driven fashion design. We present FLORA (Fashion Language Outfit Representation for Apparel Generation), the first comprehensive dataset containing 4,330 curated pairs of fashion outfits and corresponding textual descriptions.
arxiv  

Identifying the optimal dose of cannabidiol by intrabuccal administration in Kramnik (C3HeB/FeJ) mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo   +4 more
wiley   +1 more source

A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation

open access: yesAngewandte Chemie, EarlyView.
The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu   +9 more
wiley   +2 more sources

Characterization of Intestinal Flora in Osteoporosis Patients Based on 16S rDNA Sequencing

open access: yesInternational Journal of General Medicine
Mengyue Sun,1 Yuanyuan Liu,2 Shan Tang,2 Yiming Li,2 Ridong Zhang,2 Li Mao2 1Department of Geratology, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huaian, Jiangsu, 223300, People’s Republic of China; 2Department of ...
Sun M   +5 more
doaj  

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