Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu+5 more
wiley +1 more source
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog+8 more
wiley +2 more sources
Gut Flora and Urinary Phenylacetic Acid [PDF]
Edward A. Novak+2 more
openaire +6 more sources
The gut microbiota, known as the “forgotten organ” and “human second genome,” comprises a complex microecosystem. It significantly influences the development of various tumors, including colorectal, liver, stomach, breast, and lung cancers, through both ...
Xuejiao Wei+8 more
doaj
Hypertensive disorders of pregnancy (HDP) are severe complications of pregnancy with high morbidity and are a major cause of increased maternal and infant morbidity and mortality.
Min Wang+5 more
doaj +1 more source
FLORA: Formal Language Model Enables Robust Training-free Zero-shot Object Referring Analysis [PDF]
Object Referring Analysis (ORA), commonly known as referring expression comprehension, requires the identification and localization of specific objects in an image based on natural descriptions. Unlike generic object detection, ORA requires both accurate language understanding and precise visual localization, making it inherently more complex. Although
arxiv
Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? [PDF]
Sylvia Brugman+6 more
openalex +1 more source
Longitudinal Metabolomics in Amyotrophic Lateral Sclerosis Implicates Impaired Lipid Metabolism
Objective Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by altered metabolome and energy homeostasis, manifesting with body mass index changes and hypermetabolism—both prognostic of disease progression and survival.
Kai Guo+7 more
wiley +1 more source
Comment on: Brugman S et al. (2006) Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? Diabetologia 49:2105–2108 [PDF]
R. Fletcher Schwartz+4 more
openalex +1 more source
The present study employs small RNA sequencing to identify the types and content of microRNAs (miRNAs) in four widely utilized plant‐derived extracellular vesicles (pEVs). The functional annotation reveals that the pEV miRNAs are involved in regulating the progression of human cancer and viral infection, thereby demonstrating the crosskingdom ...
Fei Wang+7 more
wiley +1 more source