Results 41 to 50 of about 113,380 (310)

Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians [PDF]

, 2010
BACKGROUND: Age-related physiological changes in the gastrointestinal tract, as well as modifications in lifestyle, nutritional behaviour, and functionality of the host immune system, inevitably affect the gut microbiota, resulting in a greater ...
Nylund Lotta, Ostan, Rita, Janne Nikkïla, Elisa Pini, Elena Biagi, Rita Ostan, Daniela Monti, Pini Elisa, Satokari, Reetta, Satokari, R.M., Candela, Marco, Nylund L., Nikkilä, Janne Tapio, Nylund, Lotta, de Vos, W.M., Candela Marco, Franceschi Claudio, Willem De Vos, De Vos Willem, Brigidi, Patrizia, Nikkila J., Franceschi, C., Monti, Daniela, Marco Candela, Reetta Satokari, Bucci Laura, Vos, W.M., de, Candela, M., Pini, E., Monti, D., Pini, Elisa, Nikkïla, J., Bucci, Laura, Satokari R., Lotta Nylund, Nikkïla Janne, Satokari Reetta, Monti D., Franceschi, Claudio, Patrizia Brigidi, De Vos W., Biagi, E., Monti Daniela, Biagi Elena, Ostan Rita, Ostan, R., De Vos, Willem, Bucci, L., Laura Bucci, Brigidi, P., Nylund, L., Claudio Franceschi, Brigidi Patrizia, Biagi, Elena   +53 more
core   +1 more source

Bifidobacterium breve UCC2003 Induces a Distinct Global Transcriptomic Program in Neonatal Murine Intestinal Epithelial Cells

iScience, 2020
Summary: The underlying health-driving mechanisms of Bifidobacterium during early life are not well understood, particularly how this microbiota member may modulate the intestinal barrier via programming of intestinal epithelial cells (IECs).
Raymond Kiu, Agatha Treveil, Lukas C. Harnisch, Shabhonam Caim, Charlotte Leclaire, Douwe van Sinderen, Tamas Korcsmaros, Lindsay J. Hall   +7 more
doaj   +1 more source

Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell‐type specific manner that are altered in inflammatory bowel disease

Journal of Extracellular Vesicles, 2022
The gastrointestinal (GI) tract harbours a complex microbial community, which contributes to its homeostasis. A disrupted microbiome can cause GI‐related diseases, including inflammatory bowel disease (IBD), therefore identifying host‐microbe ...
Lejla Gul, Dezso Modos, Sonia Fonseca, Matthew Madgwick, John P. Thomas, Padhmanand Sudhakar, Catherine Booth, Régis Stentz, Simon R. Carding, Tamas Korcsmaros   +9 more
doaj   +1 more source

The Emerging Role of Bile Acids in the Pathogenesis of Inflammatory Bowel Disease

Frontiers in Immunology, 2022
Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammatory disorder of the gastrointestinal tract that arises due to complex interactions between host genetic risk factors, environmental factors, and a dysbiotic gut microbiota.
John P. Thomas, John P. Thomas, John P. Thomas, Dezso Modos, Dezso Modos, Simon M. Rushbrook, Simon M. Rushbrook, Simon M. Rushbrook, Nick Powell, Tamas Korcsmaros, Tamas Korcsmaros, Tamas Korcsmaros   +11 more
doaj   +1 more source

Gut Microbes, Diet, and Cancer [PDF]

, 2013
An expanding body of evidence supports a role for gut microbes in the etiology of cancer. Previously, the focus was on identifying individual bacterial species that directly initiate or promote gastrointestinal malignancies; however, the capacity of gut microbes to influence systemic inflammation and other downstream pathways suggests that the gut ...
Meredith A J, Hullar, Andrea N, Burnett-Hartman, Johanna W, Lampe   +2 more
openaire   +2 more sources

Gut microbiota as a source of novel antimicrobials [PDF]

, 2018
peer reviewedBacteria, Archaea, Eukarya and viruses coexist in the human gut, and this coexistence is functionally balanced by symbiotic or antagonistic relationships.
Cotter, Paul D., Enriqueta Garcia-Gutierrez, Mayer, Melinda J., Narbad, Arjan, Melinda J. Mayer, Paul D. Cotter, Arjan Narbad, Garcia-Gutierrez, Enriqueta   +7 more
core   +1 more source

Microbiota Supplementation with Bifidobacterium and Lactobacillus Modifies the Preterm Infant Gut Microbiota and Metabolome: An Observational Study

Cell Reports Medicine, 2020
Summary: Supplementation with members of the early-life microbiota as “probiotics” is increasingly used in attempts to beneficially manipulate the preterm infant gut microbiota. We performed a large observational longitudinal study comprising two preterm
Cristina Alcon-Giner, Matthew J. Dalby, Shabhonam Caim, Jennifer Ketskemety, Alex Shaw, Kathleen Sim, Melissa A.E. Lawson, Raymond Kiu, Charlotte Leclaire, Lisa Chalklen, Magdalena Kujawska, Suparna Mitra, Fahmina Fardus-Reid, Gustav Belteki, Katherine McColl, Jonathan R. Swann, J. Simon Kroll, Paul Clarke, Lindsay J. Hall   +18 more
doaj   +1 more source

Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth

iScience, 2021
Summary: The gut microbiota’s function in regulating health has seen it linked to disease progression in several cancers. However, there is limited research detailing its influence in breast cancer (BrCa).
Alastair M. McKee, Benjamin M. Kirkup, Matthew Madgwick, Wesley J. Fowler, Christopher A. Price, Sally A. Dreger, Rebecca Ansorge, Kate A. Makin, Shabhonam Caim, Gwenaelle Le Gall, Jack Paveley, Charlotte Leclaire, Matthew Dalby, Cristina Alcon-Giner, Anna Andrusaite, Tzu-Yu Feng, Martina Di Modica, Tiziana Triulzi, Elda Tagliabue, Simon W.F. Milling, Katherine N. Weilbaecher, Melanie R. Rutkowski, Tamás Korcsmáros, Lindsay J. Hall, Stephen D. Robinson   +24 more
doaj   +1 more source

Genome Characterization of a Novel Wastewater Bacteroides fragilis Bacteriophage (vB_BfrS_23) and its Host GB124

Frontiers in Microbiology, 2020
Bacteroides spp. are part of the human intestinal microbiota but can under some circumstances become clinical pathogens. Phages are a potentially valuable therapeutic treatment option for many pathogens, but phage therapy for pathogenic Bacteroides spp ...
Mohammad A. Tariq, Fiona Newberry, Fiona Newberry, Rik Haagmans, Rik Haagmans, Catherine Booth, Tom Wileman, Tom Wileman, Lesley Hoyles, Martha R. J. Clokie, James Ebdon, Simon R. Carding, Simon R. Carding   +12 more
doaj   +1 more source

Qiime Artifact eXtractor (qax): A Fast and Versatile Tool to Interact with Qiime2 Archives

BioTech, 2021
Qiime2 is one of the most popular software tools used for analysis of output from metabarcoding experiments (e.g., sequencing of 16S, 18S, or ITS amplicons). Qiime2 introduced a novel and innovative data exchange format: the ‘Qiime2 artifact’.
Andrea Telatin
doaj   +1 more source