Results 141 to 150 of about 761,618 (380)

Regulating Gut Microbiome: Therapeutic Strategy for Rheumatoid Arthritis During Pregnancy and Lactation

Frontiers in Pharmacology, 2020
Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial inflammation and bone destruction. Microbial infection is considered to be the most important inducement of RA.
Yao Yao, Xiaoyu Cai, Weidong Fei, Fujia Ren, Fengmei Wang, Xiaofei Luan, Fengying Chen, Caihong Zheng   +7 more
doaj   +1 more source

Gut microbiota of migrating wild rabbit fish (Siganus guttatus) larvae have low spatial and temporal variability [PDF]

, 2019
We investigated the gut microbiota of rabbit fish larvae at three locations in Vietnam (ThuanAn-northern, QuangNam-intermediate, BinhDinh-southern sampling site) over a three-year period. In the wild, the first food for rabbit fish larvae remains unknown,
Boon, Nico, Bossier, Peter, De Vrieze, Jo, Dierckens, Kristof, Kerckhof, Frederiek-Maarten, Lacoere, Tim, Le, Duy, Nguyen Ngoc, Dung, Nguyen, Phuoc, Vadstein, Olav   +9 more
core   +2 more sources

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Importance of good hosting: reviewing the bi-directionality of the microbiome-gut-brain-axis

Frontiers in Neuroscience
Gut microorganisms have been shown to significantly impact on central function and studies that have associated brain disorders with specific bacterial genera have advocated an anomalous gut microbiome as the pathophysiological basis of several ...
Carolina F. F. A. Costa, Carolina F. F. A. Costa, Joana Ferreira-Gomes, Joana Ferreira-Gomes, Fernando Barbosa, Benedita Sampaio-Maia, Benedita Sampaio-Maia, Philip W. J. Burnet   +7 more
doaj   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

Time to run: Late rather than early exercise training in mice remodels the gut microbiome and reduces atherosclerosis development [PDF]

, 2022
Milena Schönke, Zhixiong Ying, Artemiy Kovynev, Wietse In het Panhuis, Anne Binnendijk, Sabine van der Poel, Amanda C. M. Pronk, Trea C.M. Streefland, Menno Hoekstra, Sander Kooijman, Patrick C.N. Rensen   +10 more
openalex   +1 more source

The gut microbiome: Relationships with disease and opportunities for therapy. [PDF]

, 2019
Over the past decade, our view of human-associated microbes has expanded beyond that of a few species toward an appreciation of the diverse and niche-specialized microbial communities that develop in the human host with chronological age.
Durack, Juliana, Lynch, Susan V
core  

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Analysis of gut microbiome profiles in common marmosets (Callithrix jacchus) in health and intestinal disease [PDF]

, 2022
Alexander Sheh, Stephen C. Artim, Monika Burns, José Arturo Molina-Mora, Mary Anne Lee, JoAnn Dzink-Fox, Sureshkumar Muthupalani, James G. Fox   +7 more
openalex   +1 more source

Gut microbiome structure and metabolic activity in inflammatory bowel disease

Nature Microbiology, 2018
The inflammatory bowel diseases (IBDs), which include Crohn’s disease (CD) and ulcerative colitis (UC), are multifactorial chronic conditions of the gastrointestinal tract.
E. Franzosa, Alexandra Sirota-Madi, J. Ávila-Pacheco, Nadine Fornelos, Henry J. Haiser, S. Reinker, T. Vatanen, A. B. Hall, Himel Mallick, L. McIver, J. Sauk, R. Wilson, B. Stevens, Justin Scott, K. Pierce, A. Deik, Kevin Bullock, F. Imhann, Jeffrey A. Porter, A. Zhernakova, Jingyuan Fu, R. Weersma, C. Wijmenga, C. Clish, H. Vlamakis, C. Huttenhower, R. Xavier   +26 more
semanticscholar   +1 more source