Results 121 to 130 of about 621,850 (267)

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

Advanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song, Youwen Qin, Jiahui Luo, Liping Liu, Chenyu Luo, Yinbin Qiu, Yiyi Zhong, Huanzi Zhong, Kui Wu, Meng Ni, Dong Wu, Min Dai, Shida Zhu, Hongda Chen   +13 more
wiley   +1 more source

Gut Microbiome–Colorectal Cancer Relationship

Traditionally, the role of gut dysbiosis was thought to be limited to pathologies like Clostridioides difficile infection, but studies have shown its role in other intestinal and extraintestinal pathologies.
Devvrat Yadav, Thejus Jayakrishnan, Evgenii Filippov, Sai Gautham Kanagala, Chiranjeevi Sainatham, Syed Murtaza Ishaq   +5 more
core   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source

The Potential of Self‐Maintainable Living Materials

Advanced Science, EarlyView.
Self‐maintainable living materials are presented as the next generation of bioadaptive systems, integrating continuous sensing, decision‐making, response, self‐repair, and adaptation in a closed‐loop framework. This review highlights the design principles and emerging technologies that enable autonomous, long‐term functionality for future regenerative ...
Mohammadsadegh Nadimifar, Tatiane Eufrásio‐da‐Silva, Lidia Maeso, Gorka Orive, Alireza Dolatshahi‐Pirouz   +4 more
wiley   +1 more source

Gut Microbiome profile of Rheumatoid Arthritis in Female Patients

reservedThe aim of the study is to identify the gut microbiome of Kazakhstani female rheumatoid arthritis patients. A total of 75 female patients who met the American College of Rheumatology 2010 classification criteria for RA and 114 healthy controls ...
KOZHABERGEN, NURAY
core  

The Gut Microbiome in the First One Thousand Days of Neurodevelopment: A Systematic Review from the Microbiome Perspective

Evidence shows that the gut microbiome in early life is an essential modulator of physiological processes related to healthy brain development, as well as mental and neurodegenerative disorders.
Gabriela E. Sbardellotto, Nathalia F. Naspolini, Frederico R. Ferreira, Alline C. Campos, Carla R. Taddei, Daniel Fatori, Guilherme V. Polanczyk, Maria J. Figueiredo, Paulo A. Schüroff   +8 more
core   +1 more source

Causal relationship among the gut microbiome, short chain fatty acids and metabolic diseases

, 2020
Microbiome-wide association studies on large population cohorts have highlighted associations between the gut microbiome and complex traits, including type 2 diabetes (T2D) and obesity. However, the causal relationships remain largely unresolved.
Serena Sanna
core  

Sonogenetic Control of Engineered Probiotics for the Treatment of MASH by Modulating the Gut‐Liver Axis

Advanced Science, EarlyView.
Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji, Yan Fang, Shen Zhang, Weichen Xu, Wenyun Guo, Jing Chen, Mingrui Zhu, Congjian Wen, Siming Chen, Yuli Zhu, Huixiong Xu, Haohao Yin   +11 more
wiley   +1 more source

Epigenetics and gut microbiome of reptiles can reveal potential targets to improve human health and performance [PDF]

It is widely acknowledged that the gut microbiome plays a crucial role in both human and animal health. Nutrition, genetic predisposition, environmental factors, and epigenetic alterations significantly influence the microbiome and its interactions with ...
Alvi, A, Alhazmi, A, Alharbi, A.M., Alharbi, Ahmad M., Siddiqui, R, Khan, N., Khan, Naveed Ahmed, Alqassim, S, Alqassim, Saif, Alhazmi, Ayman, Alvi, Adeelah, Siddiqui, Ruqaiyyah   +11 more
core   +1 more source

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

Advanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim, Jiwon Lee, Minjeong Kang, Sung Sun Yim, Donghui Choe, Byung‐Kwan Cho   +5 more
wiley   +1 more source