Results 181 to 190 of about 761,618 (380)

Heat-Killed Lactiplantibacillus plantarum LRCC5314 Mitigates the Effects of Stress-Related Type 2 Diabetes in Mice via Gut Microbiome Modulation

, 2022
YoHan Nam, Seokmin Yoon, Jihye Baek, Jong‐Hwa Kim, Miri Park, Kwang‐Woo Hwang, Wonyong Kim   +6 more
openalex   +2 more sources

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

Advanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen, Qingwei Zeng, Tangchang Xu, Xinyue Qi, Kaiyi Li, Jing Wei, Liang Hao   +6 more
wiley   +1 more source

CD44 deletion leading to attenuation of experimental autoimmune encephalomyelitis results from alterations in gut microbiome in mice [PDF]

, 2017
Kumaraswamy Naidu Chitrala, Hongbing Guan, Narendra P. Singh, Philip Brandon Busbee, Alexa Orr Gandy, Pegah Mehrpouya‐Bahrami, Mitra S. Ganewatta, Chuanbing Tang, Saurabh Chatterjee, Prakash Nagarkatti, Mitzi Nagarkatti   +10 more
openalex   +1 more source

Prediction of the effects of small molecules on the gut microbiome using machine learning method integrating with optimal molecular features [PDF]

, 2023
Binyou Wang, Jianmin Guo, Xiaofeng Liu, Yang Yu, Jianming Wu, Yiwei Wang   +5 more
openalex   +1 more source

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

Science, 2018
B. Routy, E. Le Chatelier, L. Derosa, Connie P. M. Duong, M. Alou, Romain Daillère, Aurélie Fluckiger, M. Messaoudene, C. Rauber, M. Roberti, Marine Fidelle, C. Flament, Vichnou poirier-colame, P. Opolon, C. Klein, Kristina Iribarren, L. Mondragón, Nicolas Jacquelot, B. Qu, Gladys Ferrere, C. Clémenson, L. Mezquita, J. R. Masip, C. Naltet, S. Brosseau, C. Kaderbhai, C. Richard, H. Rizvi, F. Levenez, N. Galleron, B. Quinquis, N. Pons, B. Ryffel, V. Minard-Colin, P. Gonin, J. Soria, E. Deutsch, Y. Loriot, F. Ghiringhelli, G. Zalcman, F. Goldwasser, B. Escudier, M. Hellmann, A. Eggermont, D. Raoult, L. Albiges, G. Kroemer, L. Zitvogel   +47 more
semanticscholar   +1 more source

Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk

Advanced Science, EarlyView.
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu, Bingxing An, Jumei Zheng, Qiao Wang, Zhirui Yang, Zhengda Li, Dawei Liu, Fan Ying, Jie Wen, Lingzhao Fang, Guiping Zhao   +10 more
wiley   +1 more source

Gut Microbiome Composition is associated with future onset of Crohn's Disease in Healthy First-Degree Relatives.

Gastroenterology, 2023
J. R. Raygoza Garay, W. Turpin, Sun-Ho Lee, M. Smith, A. Goethel, A. Griffiths, P. Moayyedi, O. Espin‐Garcia, M. Abreu, G. Aumais, C. Bernstein, I. Biron, M. Cino, C. Deslandres, I. Dotan, W. El-Matary, B. Feagan, D. Guttman, H. Huynh, L. Dieleman, J. Hyams, K. Jacobson, D. Mack, J. Marshall, A. Otley, R. Panaccione, M. Ropeleski, M. Silverberg, A. Steinhart, D. Turner, B. Yerushalmi, A. D. Paterson, Wei Xu, K. Croitoru   +33 more
semanticscholar   +1 more source

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

Advanced Science, EarlyView.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang, Minghao Zhang, Qingbo Zheng, Qinran Yu, Guowu Yang, Wenwen Ren, Xiaoming Ma, Yongfu La, Pengjia Bao, Min Chu, Xian Guo, Chunnian Liang, Ping Yan   +12 more
wiley   +1 more source

Engineered Cancer Targeting Microbes and Encapsulation Devices for Human Gut Microbiome Applications

, 2022
Layan Hamidi Nia, Jan Claesen
openalex   +2 more sources

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

Science, 2018
V. Gopalakrishnan, C. Spencer, L. Nezi, A. Reuben, M. Andrews, T. Karpinets, P. Prieto, D. Vicente, K. Hoffman, S. Wei, Alexandria P. Cogdill, L. Zhao, C. Hudgens, D. Hutchinson, T. Manzo, M. Petaccia de Macedo, T. Cotechini, T. Kumar, W. Chen, S. Reddy, R. S. Szczepaniak Sloane, J. Galloway-Peña, H. Jiang, P. Chen, E. Shpall, K. Rezvani, A. Alousi, R. Chemaly, S. Shelburne, L. Vence, P. Okhuysen, V. B. Jensen, A. Swennes, F. McAllister, E. Marcelo Riquelme Sanchez, Y. Zhang, E. Le Chatelier, L. Zitvogel, N. Pons, J. Austin-Breneman, L. Haydu, E. Burton, J. Gardner, E. Sirmans, J. Hu, A. Lazar, T. Tsujikawa, A. Diab, H. Tawbi, I. Glitza, W. Hwu, S. Patel, S. Woodman, R. Amaria, M. Davies, J. Gershenwald, P. Hwu, J. Lee, J. Zhang, L. Coussens, Z. Cooper, P. Futreal, C. Daniel, N. Ajami, J. Petrosino, M. Tetzlaff, P. Sharma, J. Allison, R. Jenq, J. Wargo   +69 more
semanticscholar   +1 more source