Results 211 to 220 of about 746,471 (377)
W1832 Diversity in Human Gut Microbiome Composition Assessed by Pyrosequencing: Comparison of Sampling Methods
, 2010 James D. Lewis, Gary D. Wu, Yingyu Chen, Christian Hoffmann, Kyle Bittinger, Sue A. Keilbaugh, Lisa Nessel, Ronald W. Berkowsky, Jun Chen, Hongzhe Li, Frederic D. Bushman +10 moreopenalex +1 more sourceEffect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project
Nature Genetics, 2022 E. A. Lopera-Maya, A. Kurilshikov, A. van der Graaf, Shixian Hu, S. Andreu-Sánchez, Lianmin Chen, A. V. Vila, R. Gacesa, T. Sinha, V. Collij, Marjiolein A. Y. Klaassen, L. Bolte, M. F. B. Gois, Pieter B. T. Neerincx, Morris A. Swertz, Raul Patrick Lude Jan A. Esteban A. Ilja M. Serena Haro Aguirre-Gamboa Deelen Franke Kuivenhoven Lopera-Ma, Raúl Aguirre-Gamboa, Patrick Deelen, L. Franke, J. A. Kuivenhoven, I. Nolte, S. Sanna, H. Snieder, Morris A. Swertz, J. Vonk, C. Wijmenga, H. Harmsen, C. Wijmenga, Jingyuan Fu, R. Weersma, A. Zhernakova, S. Sanna +31 moresemanticscholar +1 more sourceEasyAmplicon 2: Expanding PacBio and Nanopore Long Amplicon Sequencing Analysis Pipeline for Microbiome
Advanced Science, EarlyView.EasyAmplicon 2 is an updated, user‐friendly, and community‐supported pipeline designed for full‐length amplicon data from long‐read sequencing technologies such as PacBio and Nanopore. It supports multiple platforms (Illumina, PacBio, Nanopore, etc.), integrates tools like DADA2 and Emu, and offers a complete workflow from raw data processing to high ...Hao Luo, Defeng Bai, Zhihao Zhu, Salsabeel Yousuf, Haifei Yang, Jiani Xun, Meiyin Zeng, Yao Wang, Yunyun Gao, Kai Peng, Shanshan Xu, Yuanping Zhou, Tianyuan Zhang, Chuang Ma, Huiyu Hou, Xiulin Wan, Yang Zhou, Baolei Jia, Shi Huang, Renyou Gan, Tao Wen, Tong Chen, Xia Chen, Xiaofang Li, Yong‐Xin Liu +24 morewiley +1 more sourceOrganismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins
, 2010 Peter J. Turnbaugh, Christopher Quince, Jeremiah J. Faith, Alice C. McHardy, Tanya Yatsunenko, Faheem Niazi, Jason P. Affourtit, Michael D. Miller, Bernard Henrissat, Rob Knight, Jeffrey I. Gordon +10 moreopenalex +1 more sourceT‐2 Toxin Exploits Gut‐Derived Staphylococcus Saprophyticus to Disrupt Hepatic Macrophage Homeostasis
Advanced Science, EarlyView.T‐2 toxin promotes the proliferation of intestinal S. saprophyticus and facilitates its translocation to the liver in piglets and mice. The translocated bacteria trigger autophagy in Kupffer cells and recruit monocytes to the liver through the nucleotide‐binding oligomerization domain 2 (NOD2) signaling pathway, alongside the M1 polarization of hepatic Yuanyuan Zhu, Liu Xu, Fangrui Guo, Jianyu Qu, Xiangyan Liu, Qiurong Xu, Jie Sheng, Jiangping Wang, Xiaohong Xie, Ruimin Ren, Chuan Zhou, Sisi Yan, Shuiping Liu, Zhihang Yuan, Rongfang Li, Jing Wu, Jine Yi, Yulong Yin, Lixin Wen, Ji Wang +19 morewiley +1 more sourceThe High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track
Advanced Science, EarlyView.In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and Chun Huang, Minghao Zhang, Qingbo Zheng, Qinran Yu, Guowu Yang, Wenwen Ren, Xiaoming Ma, Yongfu La, Pengjia Bao, Min Chu, Xian Guo, Chunnian Liang, Ping Yan +12 morewiley +1 more sourceDecoding a Gut Commensal Signal: Structural and Immunological Profiling of Segatella Copri Lipopolysaccharide
Angewandte Chemie, EarlyView.The lipopolysaccharide (LPS) of Segatella copri is a structurally unique, immunomodulatory glycoconjugate. Combining mass spectrometry (MS), nuclear magnetic resonance (NMR), and cytometry by time‐of‐flight (CyTOF), we uncover a rough‐type LPS with reduced TLR4 agonism and selective monocyte effects, further highlighting the key role of LPS chemistry ...Luca De Simone Carone, Giusi Barra, Roberta Cirella, Marcello Ziaco, Marcello Mercogliano, Francesca Olmeo, Emanuela Andretta, Valentina Mazziotti, Carmela Fusco, Giuliana D'Ippolito, Katarzyna Anna Duda, Freda M. Farquharson, Petra Louis, Angelo Fontana, Alba Silipo, Antonio Molinaro, Fabrizio Chiodo, Flaviana Di Lorenzo +17 morewiley +2 more sourcesMedicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis
Advanced Science, EarlyView.This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi +8 morewiley +1 more source
