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The gut microbiome and its use as a target for novel therapeutic modalities [PDF]
The human microbiome is the complete microorganisms in addition to their genes inhabiting the human body. The gut microbiome is the most important part of the human microbiome. The gut microbiome performs many benefits to the host.
Ayman Allam, Ahmad Al-Shaar
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Preterm gut microbiota and metabolome following discharge from intensive care [PDF]
The development of the preterm gut microbiome is important for immediate and longer-term health following birth. We aimed to determine if modifications to the preterm gut on the neonatal intensive care unit (NICU) impacted the gut microbiota and ...
Berrington, Janet+8 more
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Radiotherapy and the gut microbiome: facts and fiction
An ever-growing body of evidence has linked the gut microbiome with both the effectiveness and the toxicity of cancer therapies. Radiotherapy is an effective way to treat tumors, although large variations exist among patients in tumor radio ...
Jing Liu, Chao Liu, Jinbo Yue
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The precise mechanisms of action of the host’s gut microbiome at the level of its constituting bacteria are obscure in most cases despite its definitive role.
Chongkai Zhai+5 more
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Immunoglobulin A and liver diseases. [PDF]
Immunoglobulin A (IgA) is a major immunoglobulin isotype in the gut and plays a role in maintenance of gut homeostasis. Secretory IgA (SIgA) has multiple functions in the gut, such as to regulate microbiota composition, to protect intestinal epithelium ...
Inamine, Tatsuo, Schnabl, Bernd
core +2 more sources
From taxonomy to metabolic output: what factors define gut microbiome health?
Many studies link the composition of the human gut microbiome to aberrant health states. However, our understanding of what constitutes a ‘healthy’ gut ecosystem, and how to effectively monitor and maintain it, are only now emerging.
Tomasz Wilmanski+4 more
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Background The gut microbiome is altered in chronic kidney disease (CKD), potentially contributing to CKD progression and co-morbidities, but population-based studies of the gut microbiome across a wide range of kidney function and damage are lacking ...
Brandilyn A. Peters+12 more
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The gut-cardiovascular connection: new era for cardiovascular therapy
Our gut microbiome is constituted by trillions of microorganisms including bacteria, archaea and eukaryotic microbes. Nowadays, gut microbiome has been gradually recognized as a new organ system that systemically and biochemically interact with the host.
Cheng Chak Kwong, Huang Yu
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The gut microbiome is important for host nutrient metabolism and ecological adaptation. However, how the gut microbiome is affected by host phylogeny, ecology and diet during sympatric speciation remain unclear.
Zhuoran Kuang+5 more
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Relationship between the gut microbiome and the development of colorectal cancer [PDF]
Colorectal cancer (CRC) is one of the leading cancers in the world. With the influence of westernized lifestyle, the morbidity and mortality of CRC are on the rise in China.
Yang-Ting HE, Li LIU
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