Results 41 to 50 of about 169,444 (261)
Gut microbiome and fecal metabolite profiles in obese school-aged children from Northern Thailand
Frontiers in MicrobiologyAlthough the gut microbiota of school-aged children has been extensively studied, there is a significant lack of knowledge regarding the relationship between fecal metabolite profiles and the gut microbiota in the context of obesity in young children ...
Phatthanaphong Therdtatha +10 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Gut Microbes, 2023 Background The gut microbiome is altered in chronic kidney disease (CKD), potentially contributing to CKD progression and co-morbidities, but population-based studies of the gut microbiome across a wide range of kidney function and damage are lacking ...
Brandilyn A. Peters +12 more
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Journal of the Formosan Medical Association, 2019 Obesity is worldwide epidemic given its rapid growth in global prevalence. Among the risk factors contributing to obesity, human gut microbiome recently emerges with unprecedented intimacy in host metabolism and inflammation. With the advances in sequencing technology, more and more detailed understandings towards the intricate relationships linking ...
Ching-Hung Tseng, Chun-Ying Wu
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
MicroorganismsAge-related changes in the gut significantly impact host health, yet the multi-omics dynamics during the maturation of Tibetan pigs remain unclear.
Mengshi Zhao +7 more
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Radiotherapy and the gut microbiome: facts and fiction
Radiation Oncology, 2021 An ever-growing body of evidence has linked the gut microbiome with both the effectiveness and the toxicity of cancer therapies. Radiotherapy is an effective way to treat tumors, although large variations exist among patients in tumor radio ...
Jing Liu, Chao Liu, Jinbo Yue
doaj +1 more source
Gut Microbiome Structure and Association with Host Factors in a Korean Population
mSystems, 2021 Characterizing the gut microbiome in the healthy population is the first step in elucidating its associations with host health conditions. Populations with different diet patterns, lifestyles, and genetic backgrounds harbor different gut microbes.
Mi Young Lim +6 more
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Journal of Menopausal MedicineEstrogens are steroid hormones that are involved in regulating the growth, development, and functioning of the human reproductive system as well as in controlling the neuroendocrine, skeletal, adipogenesis, and cardiovascular systems. Estrogen is released into the bloodstream in two different states: as a free hormone or in association with proteins ...
Seung-Lee Park, Min-Sun Kim, Tae-Hee Kim
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source