Results 51 to 60 of about 285,342 (295)
From taxonomy to metabolic output: what factors define gut microbiome health?
Gut Microbes, 2021 Many studies link the composition of the human gut microbiome to aberrant health states. However, our understanding of what constitutes a ‘healthy’ gut ecosystem, and how to effectively monitor and maintain it, are only now emerging.
Tomasz Wilmanski +4 more
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Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Gut microbiome and fecal metabolite profiles in obese school-aged children from Northern Thailand
Frontiers in MicrobiologyAlthough the gut microbiota of school-aged children has been extensively studied, there is a significant lack of knowledge regarding the relationship between fecal metabolite profiles and the gut microbiota in the context of obesity in young children ...
Phatthanaphong Therdtatha +10 more
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Radiotherapy and the gut microbiome: facts and fiction
Radiation Oncology, 2021 An ever-growing body of evidence has linked the gut microbiome with both the effectiveness and the toxicity of cancer therapies. Radiotherapy is an effective way to treat tumors, although large variations exist among patients in tumor radio ...
Jing Liu, Chao Liu, Jinbo Yue
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Gut Microbes, 2023 Background The gut microbiome is altered in chronic kidney disease (CKD), potentially contributing to CKD progression and co-morbidities, but population-based studies of the gut microbiome across a wide range of kidney function and damage are lacking ...
Brandilyn A. Peters +12 more
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FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare
Frontiers in Pharmacology, 2020 Advances in systems biology, particularly based on the omics approaches, have resulted in a paradigm shift in both traditional Chinese medicine (TCM) and the gut microbiome research.
Runzhi Zhang +3 more
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Gut microbiome of migratory shorebirds: Current status and future perspectives
Ecology and Evolution, 2021 Migratory shorebirds have many unique life history characteristics, such as long‐distance travel between breeding sites, stopover sites, and wintering sites.
Zheng Zhang, Zhisong Yang, Lifeng Zhu
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Gut Microbiome Structure and Association with Host Factors in a Korean Population
mSystems, 2021 Characterizing the gut microbiome in the healthy population is the first step in elucidating its associations with host health conditions. Populations with different diet patterns, lifestyles, and genetic backgrounds harbor different gut microbes.
Mi Young Lim +6 more
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source