Results 131 to 140 of about 693,536 (346)
The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song+13 more
wiley +1 more source
Erratum to âMolecular analysis of bacterial microbiota in the gut of the termite Reticulitermes speratus (Isoptera; Rhinotermitidae)â [PDF]
Yuichi Hongoh+2 more
openalex +1 more source
Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu+7 more
wiley +1 more source
Influence of mode of delivery on gut microbiota composition in seven year old children [PDF]
Seppo Salminen
openalex +1 more source
Gut microbiota functions: metabolism of nutrients and other food components
The diverse microbial community that inhabits the human gut has an extensive metabolic repertoire that is distinct from, but complements the activity of mammalian enzymes in the liver and gut mucosa and includes functions essential for host digestion. As
I. Rowland+6 more
semanticscholar +1 more source
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie+9 more
wiley +1 more source
Background The Asia-Pacific Colorectal Screening (APCS) score is effective to screen high-risk groups of advanced colorectal neoplasia (ACN) patients but needs revising and can be combined with the fecal immunochemical test (FIT).
Xu-xia He+14 more
doaj +1 more source
Novel Evidence Suggesting Clostridium difficile Is Present in Human Gut Microbiota More Frequently than Previously Suspected [PDF]
Masahiro Iizuka+9 more
openalex +1 more source
Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu+8 more
wiley +1 more source
Summary: Obesity is associated with altered gut microbiome composition but data across different populations remain inconsistent. We meta-analyzed publicly available 16S-rRNA sequence datasets from 18 different studies and identified differentially ...
Yu Lin+7 more
doaj